Alfree Capsule (Omeprazole)

Adult dose

◎ Adults 1) Gastric ulcer: Administer omeprazole 20mg orally once daily. Most cases may heal within 4 weeks, although the healing period may occasionally vary by patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to treatment with other preparations, administration of 40mg once daily generally results in healing within 8 weeks, although the healing period may occasionally vary by patient. If recurrence occurs, repeat treatment. 2) Short-term treatment of duodenal ulcer: Administer 20mg orally once daily. Most cases may heal within 2 weeks, although the healing period may occasionally vary by patient. If healing is not complete after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to treatment with other preparations, administration of 40mg once daily generally results in healing within 4 weeks, although the healing period may occasionally vary by patient. If recurrence occurs, repeat treatment. 3) Treatment of reflux esophagitis and symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): - Reflux esophagitis: Administer 20mg orally once daily. Most cases may heal within 4 weeks, although the healing period may occasionally vary by patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to treatment with other preparations, administration of 40mg once daily generally results in healing within 8 weeks, although the healing period may occasionally vary by patient. If recurrence occurs, repeat treatment. - Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily. Treatment for 2～4 weeks is generally sufficient for healing. 4) Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to heal: Administer 20mg orally once daily. If recurrence occurs, the dose may be increased to 40mg once daily. 5) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose as appropriate for each individual. More than 90% of patients may respond to doses of 20 - 120mg daily; when doses of 80mg or more are administered daily, divide the dose into 2 administrations per day. 6) Combination therapy with antibiotics to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this medicine 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this medicine 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the therapeutic effect is insufficient, omeprazole monotherapy may be continued. 7) Treatment of gastric/duodenal ulcers or erosions caused by administration of nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases may heal within 4 weeks, although the healing period may occasionally vary by patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 8) Maintenance therapy for prevention of gastric/duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID administration in patients receiving long-term NSAID treatment who have a history of gastric/duodenal lesions: Administer 20mg orally once daily. 9) Prevention of recurrence of reflux esophagitis: Administer 10mg orally once daily to prevent recurrence of reflux esophagitis. * When taking this medicine, swallow it whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication is used to treat gastrointestinal diseases by reducing gastric acid. It should not be administered to patients who are allergic to its components or to patients with suspected malignant gastric ulcers. Caution is needed as the use of this medication in patients with malignant tumors can lead to symptom relief that may delay diagnosis. Also, it cannot be combined with certain antiviral agents and some antibiotics, so it must be discussed with healthcare professionals. Patients with impaired liver function or the elderly should have their doses adjusted, and in cases of severe liver dysfunction, it should not exceed 20 mg per day. While taking this medication, neurological symptoms such as headaches, drowsiness, dizziness, insomnia may occur, and in severe cases, confusion or hallucinations can rarely occur. Liver enzyme levels may increase, so if there are signs of liver dysfunction, administration must be stopped immediately. In the gastrointestinal tract, diarrhea, constipation, nausea, vomiting, and abdominal pain may commonly occur, and dry mouth or stomatitis may occur rarely. Severe skin reactions such as skin rashes, itching, and in severe cases, Stevens-Johnson syndrome may appear, so if any skin abnormalities occur, the medication should be stopped immediately. Rarely, hypersensitivity reactions such as angioedema and shock may occur, so caution is advised. Long-term use may increase the risk of fractures and hypomagnesemia may occur, so regular testing is necessary. This medication lowers gastric acidity, which can increase the risk of certain bacterial infections, so if diarrhea persists, medical consultation should be sought. During pregnancy, it should be used cautiously only when necessary, as it may affect the fetus, and during lactation, it is better to avoid administration or discontinue breastfeeding. Safety in children has not been established, so it is preferable not to use it in children. In cases of overdose, symptoms such as vomiting, dizziness, abdominal pain, and headaches may occur, but most are temporary and severe symptoms are rare. Keep out of reach of children, do not transfer to another container, and store it tightly closed after use. This medication may increase the risk of tumors in the stomach due to long-term use, so regular check-ups are necessary during long-term administration.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling of faintness, vertigo, confusion, agitation, aggressiveness, hallucination, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, fluid retention, constipation, nausea, vomiting, abdominal pain, abdominal distension, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, fatigue, peripheral edema, increased sweating, blurred vision, vision impairment, taste disorder, female breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms, systemic lupus erythematosus, discoid lupus erythematosus, gastric fundic polyps, hypocalcemia, hypokalemia, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, acute interstitial nephritis, nausea, apathy

This medication is sensitive to air and moisture, so it must be stored in an airtight container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

A hard capsule with an upper reddish-brown and lower pink color, filled with yellowish enteric-coated granules.

Package unit

28 capsules/bottle