Numesartan Tablet 20mg (Olmesartan Medoxomil)

Adult dose

For adults, the recommended starting dose is 10mg once daily, regardless of meals. If blood pressure is not adequately controlled at this dose, it can be increased to 20mg once daily, with a maximum daily dose of 40mg. The antihypertensive effect can be seen within 2 weeks of starting treatment, with maximum effect appearing around 8 weeks. If blood pressure is not controlled with monotherapy, it may be combined with thiazide diuretics such as hydrochlorothiazide.

Child dose

The safety and efficacy in children have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients who are allergic to any component of this medication, pregnant women, and breastfeeding women should not take it, and it is also safe for patients undergoing kidney dialysis, those with severe liver disease, or those with biliary obstruction. Patients with genetic issues such as lactose intolerance should avoid taking this medication due to the lactose it contains. Patients with low blood volume or low body sodium may experience symptoms of hypotension when taking this medication for the first time, so their condition should be thoroughly checked before taking it and appropriate measures taken if necessary. Patients with impaired kidney function should have their kidney function monitored periodically while taking this medication, and it is not recommended for patients with severe kidney impairment or kidney transplant recipients. Particularly for patients with issues in kidney blood vessels, care should be taken as kidney function deterioration may occur. This medication can increase potassium levels, so patients with heart or kidney diseases should regularly monitor their serum potassium concentration. Patients with aortic stenosis, mitral stenosis, or obstructive heart disease should be especially cautious when taking this medication. Due to its blood pressure-lowering action, dizziness may occur, so caution should be exercised when driving or operating hazardous machinery. The antihypertensive effects of this medication may vary among certain ethnic groups, so individual responses should be monitored. Dizziness, headache, palpitations, abdominal pain, rash, and other symptoms may occur during use, and serious side effects such as liver function abnormalities or angioedema have been reported rarely. If symptoms such as chronic diarrhea, abdominal pain, or vomiting persist, discontinuation of the medication and consultation with a doctor are advised. When taking other antihypertensives, potassium supplements, diuretics, etc., the risk of side effects may increase due to interactions, so patients should inform their doctors and take caution. Pregnant women should avoid taking this medication for the health of the fetus, and breastfeeding women should consider cessation of breastfeeding as adverse reactions may occur in infants. The safety of this medication in children has not been established; therefore, it should be used cautiously in children. In case of overdose, symptoms such as hypotension, palpitations, bradycardia may appear, so if such symptoms occur, immediate medical assistance should be sought.

Serious side effects

Hives, severe swelling (angioedema, facial swelling, peripheral edema), chest pain, difficulty breathing, angioedema, anaphylaxis reaction, severe skin reactions, severe allergic reactions, chronic malabsorption (sprue)-like intestinal disease, intestinal vascular edema, rhabdomyolysis, hyperkalemia, acute renal failure, increased serum creatinine, hives, liver function abnormalities (abnormal liver function tests, autoimmune hepatitis), hypotension, hypotension symptoms

Mild side effects

• Dizziness
• headache
• palpitations
• lower back pain
• bronchitis
• increase in creatine kinase
• diarrhea
• hematuria
• hyperglycemia
• hypertriglyceridemia

This medication should be stored in a sealed container to protect it from exposure to air or moisture. The appropriate storage temperature is between 1°C and 25°C in a cool place.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle