Adrazo (Amlodipine Besylate)

Adult dose

Administer amlodipine 5 mg orally once daily, which can be increased to a maximum of 10 mg daily based on patient response. Adjust according to age and symptoms.

This drug should not be administered to certain patients. Individuals allergic to this drug or similar drugs, those who are breastfeeding, patients with severe liver dysfunction, those with severe aortic stenosis, and individuals in shock should not use this medication. There are also cases where this drug should be used with caution. Caution is needed when using this drug in patients with severe hypotension, those requiring dialysis due to renal failure, elderly patients, and women who are pregnant or may become pregnant. When using this medication, various side effects may occur. The most common side effects include facial flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, hypotension, vasculitis, sensory abnormalities, fainting, erectile dysfunction, gynecomastia, dry mouth, dyspepsia, pancreatitis, weight changes, arthralgia, muscle cramps, decreased blood cell count, insomnia, skin rash, and hair loss have been reported. If severe side effects occur, immediate consultation with a healthcare professional is required. This drug requires special caution for patients with heart failure or impaired liver function. In patients with poor liver function, the half-life of the drug in the body may be prolonged, necessitating dose adjustments. This drug takes effect slowly and is not suitable for the urgent treatment of heart diseases. The effect on driving or operating machinery is minimal. This drug may interact with other medications, so it is essential to inform your healthcare provider about any other medications you are taking. In particular, consuming grapefruit juice may enhance the blood pressure-lowering effect, so it is advisable to avoid concurrent consumption. Additionally, when used alongside certain antibiotics, antihypertensives, and immunosuppressants, dose adjustments or caution may be necessary. Women who are pregnant or breastfeeding should avoid using this drug unless absolutely necessary, as its safety during pregnancy and lactation has not been established. If breastfeeding, it is recommended to discontinue nursing while taking this drug. Use in children under 6 years of age is not recommended, as safety and efficacy have not been confirmed for this age group. In cases of overdose, severe hypotension and shock may occur, requiring immediate emergency intervention. In the event of overdose, gastric lavage or activated charcoal may be beneficial, and cardiac and respiratory function should be monitored continuously. This drug is not removed by hemodialysis, so specific treatment is necessary in cases of overdose.

Serious side effects

• Hives
• severe swelling (edema)
• hepatitis
• jaundice
• toxic epidermal necrolysis
• severe allergic reactions
• severe skin reactions
• severe edema
• or urination abnormalities.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be kept in a tightly sealed container to protect it from air and moisture. It is important to maintain storage temperatures in the range of 1 to 30 degrees Celsius.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle