Medication info
Unisium Tablet 20mg (Esomeprazole Magnesium Trihydrate)

Unisium Tablet 20mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›21.69mg / 1 tablet
Manufacturer / importer
한국유니온제약(주)
Appearance
Pale pink round film-coated tablet
Packaging
28T (14T/PTP X 2)
Approval status
Active

MFDS item code 201507786 · Approved 2015.11.20 · Insurance code 665506780

Summary

Main use
Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment of Helicobacter pylori positive peptic ulcer, alleviation of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - For treatment of erosive esophagitis: 40 mg once daily for 4 weeks - For continued treatment of erosive esophagitis: additional 4-week course - Maintenance therapy for recurrence prevention: 20 mg once daily - For treatment of gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily
Children's dosage
Adolescents aged 12 years and older - For the treatment of erosive esophagitis: 40 mg once daily for 4 weeks - For continued treatment: additional 4-week course - For gastroesophageal reflux disease without esophagitis: 1 day

Ingredients

Manufacturer
한국유니온제약(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment of Helicobacter pylori positive peptic ulcer, alleviation of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • rebleeding of gastric ulcers
View approved original text

This medicine is used to treat gastroesophageal reflux disease and erosive esophagitis, as well as to prevent the recurrence of esophagitis. It also helps alleviate symptoms of gastroesophageal reflux disease without esophagitis. It is effective in the treatment and prevention of duodenal ulcers and peptic ulcers in combination with antibiotics for Helicobacter pylori eradication. Additionally, it is used for treating upper gastrointestinal symptoms related to the administration of nonsteroidal anti-inflammatory drugs (including COX-2) and in the treatment of gastric ulcers, and for the prevention of gastric ulcers and duodenal ulcers. It is beneficial in the treatment of Zollinger-Ellison syndrome and maintenance therapy after inducing prevention of rebleeding from gastric or duodenal ulcers. It is widely used for the treatment and prevention of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - For treatment of erosive esophagitis: 40 mg once daily for 4 weeks - For continued treatment of erosive esophagitis: additional 4-week course - Maintenance therapy for recurrence prevention: 20 mg once daily - For treatment of gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily

Children's dosage

Adolescents aged 12 years and older - For the treatment of erosive esophagitis: 40 mg once daily for 4 weeks - For continued treatment: additional 4-week course - For gastroesophageal reflux disease without esophagitis: 1 day

Precautions

This medication should not be used in patients with known allergies to specific ingredients or drugs, or a history of such reactions. It should be avoided in patients with a history of myocardial infarction or those who are breastfeeding. This medication may cause various side effects, including headache, abdominal pain, diarrhea, skin rash, muscle pain, among others, so if symptoms are severe or persistent, consult a physician. If used for a long time, it is important to undergo regular examinations to monitor health status. This medication may interact with other drugs, so if you are currently taking medication, be sure to inform your doctor or pharmacist. Particularly, caution is required when taken with certain antibiotics or antivirals, and some drugs should be avoided in combination. The safety of this medication during pregnancy has not been fully established, so it should be used carefully as directed by a doctor. It is advisable not to use this medication while breastfeeding, as it may pass into breast milk. In case of overdose, there is no specific antidote, so seek immediate medical attention for appropriate treatment. This medication should be kept out of reach of children, and care should be taken not to transfer it to other containers to avoid deterioration in quality or accidents.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe hypomagnesemia, microscopic colitis, jaundice, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disturbances, blurred vision, bronchospasms, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, fatigue, increased sweating, Clostridium difficile-associated diarrhea, abdominal distension, allergic reactions, back pain, chest pain, sternal pain, facial swelling, flushing,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, it is best to keep it at room temperature between 1 and 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

Pale pink round film-coated tablet

Package unit

28T (14T/PTP X 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.