Unisium Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid such as water and must not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. - If esophagitis is untreated or symptoms persist, continue for an additional 4 weeks. - Maintenance therapy for prevention of recurrence: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily.

Children's dosage

For adolescents aged 12 and older 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. - If symptoms persist or are not treated, continue for an additional 4 weeks.

This medication should not be administered to patients who are hypersensitive to certain ingredients or benzimidazole derivatives. Patients with hypersensitivity to penicillin or macrolide antibiotics should also be cautious. Special caution should be taken during combination therapy for eradication of Helicobacter pylori. Additionally, this medication is not to be administered to patients taking certain heart-related medications or antivirals, nursing women, or those with a history of myocardial infarction. Uncommon adverse reactions may occur in various systems including blood, immune, metabolic, psychiatric, neurological, gastrointestinal, liver, skin, etc., so patients should consult a physician if any abnormal symptoms arise. Prolonged use may lead to electrolyte imbalances such as hypomagnesemia, necessitating regular testing. This medication can suppress gastric acid secretion, increasing the risk of bacterial overgrowth in the stomach, so if diarrhea persists, it should be reported to healthcare professionals. Due to numerous drug interactions, patients must consult a physician or pharmacist when taking with other medications, especially antivirals, anticoagulants, and certain antibiotics. Its safety during pregnancy has not been fully established, so it should only be used cautiously when necessary, and it should not be used during breastfeeding. In case of overdose, as there is no specific antidote, patients should seek immediate treatment from medical institutions. It is safe to store out of reach of children and not transfer into other containers.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe hypomagnesemia, mental confusion, pancreatitis, jaundice, hepatitis, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, rhabdomyolysis, Clostridium difficile-associated diarrhea, severe.

Mild side effects

• Headache
• dizziness
• paresthesia
• drowsiness
• taste disturbance
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablet

Package unit

28T (14T/PTP X 2)