Nexav 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid, such as water, and should not be chewed or crushed. 1) Treatment of gastroesophageal reflux disease: 40 mg once daily for 4 weeks; if erosive reflux esophagitis is not improved or symptoms persist, an additional 4 weeks of treatment. 2) Long-term maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. 3) Symptom management for gastroesophageal reflux disease without esophagitis: once daily.

Children's dosage

Adolescents aged 12 years and older 1) Treatment of gastroesophageal reflux disease: 40 mg once daily for 4 weeks; if symptom persists or erosive reflux esophagitis is not improved, an additional 4 weeks of treatment. 2) Esophagitis

This medication should not be administered to specific patients. For instance, individuals who are allergic to this medication or its ingredients or who have allergies to certain antibiotics should not take it. Moreover, it is also advisable for individuals with heart diseases or those who are breastfeeding to refrain from using this medication. While taking this medication, various side effects may occur, so caution is advised. Common side effects may include headaches, abdominal pain, and diarrhea, and rarely blood disorders or severe allergic reactions may occur. Long-term use may lead to electrolyte abnormalities such as hypomagnesemia; thus, regular examinations are necessary. As this medication suppresses gastric acid secretion, it may increase bacterial growth in the gastrointestinal tract, making it important to consult a healthcare professional if diarrhea persists. Furthermore, long-term use may increase the risk of fractures, so patients at risk for osteoporosis should be cautious. This medication may interact with other drugs; therefore, if you are taking other medications, it is essential to inform your doctor or pharmacist. Special caution is required when used alongside antiviral medications, antibiotics, anticoagulants, etc., due to the potential risk of side effects from changes in blood concentration. During pregnancy, the safety data for this medication is limited; thus, pregnant women should use it cautiously after consulting with their doctors. It is recommended that breastfeeding women do not take this medication. In cases of overdose, there is no specific antidote, so it is imperative to visit a medical institution immediately for appropriate treatment, and keep it in a secure place out of the reach of children.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis reaction, shock, severe allergic reactions with high fever, severe rashes, blisters, peeling skin, pain in mucous membranes of mouth/eyes, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe cutaneous adverse reactions, dyspnea, asthma attacks, bronchospasm, jaundice of skin or eyes

Mild side effects

Headache, dizziness, paresthesia, drowsiness, insomnia, anxiety, confusion, depression, aggression, hallucinations, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, fracture, arthralgia, myalgia, muscle weakness, asthenia, increased sweating, Clostridium difficile-associated diarrhea, abdominal distension, allergic reactions, back pain,

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is crucial to maintain the storage temperature between 1 to 30 degrees Celsius to preserve the drug's effectiveness and safety for an extended period.

Appearance

Pink round film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle