Arotin Tablet 10 mg (Atorvastatin Calcium Trihydrate)

Adult dosage

For hyperlipidemia: The recommended starting dose is 10 mg of atorvastatin once daily; for patients needing more significant LDL cholesterol reduction, it may start at 20 mg or 40 mg once daily. This medication is administered once daily within a dose range of 10 to 80 mg. Initial and maintenance doses should be individualized based on therapeutic goals and responses, with lipid levels analyzed and dosage adjusted within 2–4 weeks after initiation or dose modification.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17): The recommended starting dose is 10 mg once daily, with a maximum recommended dose of 20 mg once daily. The dosage may be adjusted according to therapeutic goals.

This medication may cause muscle abnormalities; therefore, it should be discontinued immediately if muscle pain or weakness worsens or if creatine kinase levels rise significantly. This medication should not be used in patients with specific diseases or conditions, such as liver disease, muscle disorders, pregnant or breastfeeding women, children under 10 years of age, and patients taking certain medications. Patients with liver or kidney dysfunction should be particularly cautious when using this medication and should have regular liver function and muscle-related tests. During treatment, if symptoms such as muscle pain, fatigue, or fever occur, patients must inform healthcare professionals immediately, and blood tests may be done to check the condition. Moreover, this medication can interact with several other drugs, so it is essential to inform healthcare professionals if taking other medications, particularly with certain antibiotics, antifungals, and HIV treatments. Pregnant women or those who could become pregnant should not use this medication and should employ appropriate contraception during treatment. Breastfeeding women should also avoid taking this medication, and children or the elderly should use it cautiously due to a higher risk of side effects. As there is no specific antidote for overdose, treatment should be symptomatic, and liver function and muscle status should be monitored periodically. This medication should be stored out of reach of children and in its original container for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain of oral/ocular mucosa, shortness of breath or breathing difficulties, asthma attack, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues.

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to prevent air or moisture entry. It should also be kept in a place that avoids extremes of temperature, ideally between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle