Medication info
Omes Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Omes Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg / 1 tablet
Manufacturer / importer
삼익제약(주)
Appearance
Pink round film-coated tablet
Packaging
28 tablets (14 tablets/Alu-Alu X 2, 7 tablets/Alu-Alu X 4)
Approval status
Active

MFDS item code 201507736 · Approved 2015.11.17 · Insurance code 644003700

Summary

Main use
Improvement of gastrointestinal diseases such as treatment and prevention of recurrence of gastroesophageal reflux disease (erosive reflux esophagitis), and treatment of Helicobacter pylori positive peptic ulcers.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, take for an additional 4 weeks. - Maintenance therapy for prevention of esophagitis recurrence: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: once daily,
Children's dosage
Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, an additional 4 weeks of treatment is required.

Ingredients

Manufacturer
삼익제약(주)

Efficacy & effects

Improvement of gastrointestinal diseases such as treatment and prevention of recurrence of gastroesophageal reflux disease (erosive reflux esophagitis), and treatment of Helicobacter pylori positive peptic ulcers.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • gastric ulcer rebleeding
View approved original text

This medication is used for the treatment and symptom relief of gastroesophageal reflux disease, particularly erosive reflux esophagitis. It is also included in antibiotic combination therapy for the eradication and prevention of recurrence in patients with Helicobacter pylori-associated peptic ulcers. It helps alleviate upper gastrointestinal symptoms in patients taking non-steroidal anti-inflammatory drugs and treats and prevents gastric and duodenal ulcers. Additionally, it is effective in treating Zollinger-Ellison syndrome and for maintenance therapy following ulcer rebleeding. Overall, it is used for the treatment of various gastrointestinal-related diseases and symptom improvement.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, take for an additional 4 weeks. - Maintenance therapy for prevention of esophagitis recurrence: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: once daily,

Children's dosage

Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, an additional 4 weeks of treatment is required.

Precautions

This medication should not be used by certain patients. Patients who are hypersensitive to this medication or its components, or have a history of hypersensitivity to benzimidazole derivatives should not take it. Additionally, patients with hypersensitivity to penicillins or macrolide antibiotics should not be treated when combined with amoxicillin or clarithromycin for the eradication of Helicobacter pylori. Patients with a history of myocardial infarction or those who are breastfeeding should also avoid this medication. This medication can cause various adverse reactions. The most common symptoms include headache, abdominal pain, diarrhea, nausea, and vomiting, and dizziness or insomnia may occasionally occur. Rarely, blood abnormalities, hypomagnesemia, liver function abnormalities, skin rashes, and myalgia have been reported. In severe cases, serious side effects such as anaphylactic shock, Stevens-Johnson syndrome, and liver failure may occur, so if symptoms appear, immediate medical attention is required. Prolonged use may conceal symptoms of malignant tumors, so if weight loss, recurrent vomiting, or hematemesis occur, it is essential to consult a doctor. It is important to undergo regular examinations if taken for more than one year. This medication suppresses gastric acid, which may slightly increase the risk of diarrhea or gastrointestinal infections. This drug may interact with other medications, so caution is advised, especially when taking antiviral drugs, antibiotics, warfarin, methotrexate, clopidogrel, etc. The effects of drugs taken together with this medication may increase or decrease, so it is necessary to inform and consult with the doctor or pharmacist about all medications being taken. There is limited data on the safety of this drug during pregnancy, so pregnant women should consult a doctor before taking it, and breastfeeding women are advised not to take this medication. There is no specific antidote for overdose, so it is essential to visit a medical institution immediately for appropriate treatment, as this drug binds strongly to blood proteins and is not removed by dialysis. This medication should be kept out of the reach of children and care should be taken when transferring to another container as it may cause quality degradation or accidents.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, shock, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, and overall

Mild side effects

  • Headache
  • dizziness
  • sensory disturbances
  • drowsiness
  • taste disorders
  • blurred vision
  • bronchospasm
  • abdominal pain
  • constipation
  • diarrhea
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  • abdominal bloating
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • increased liver enzymes
  • dermatitis
  • itching
  • rash
  • hair loss
  • photosensitivity
  • fractures
  • arthralgia
  • myalgia
  • weakness
  • increased sweating
  • tachycardia
  • flushing
  • hypertension
  • fatigue
  • fever
  • malaise
  • pain
  • decreased appetite
  • insomnia
  • migraine
  • visual field defects
  • dysmenorrhea
  • acne
  • hives

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is advisable to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the drug's efficacy and prevents degradation.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2, 7 tablets/Alu-Alu X 4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.