Vigliptin Duo Tablets 50/850 mg

Adult dose

This medication is generally taken twice a day with food; the dosage should be gradually increased to reduce gastrointestinal adverse effects associated with metformin. 1. For patients currently not receiving treatment with metformin: The initial dose is 50/500 mg taken twice a day, one tablet at a time; it can be increased to 50/1000 mg taken twice a day, one tablet at a time. 2. For patients receiving treatment with metformin:

This medication is used for the treatment of diabetes and aids in blood sugar control. During the course of taking this medication, allergic reactions may occur; if symptoms such as skin rash, itching, or swelling occur, immediately discontinue use and consult a physician. Severe inflammation of the pancreas, known as acute pancreatitis, may occur; if symptoms such as abdominal pain, nausea, or vomiting arise, seek medical attention immediately. Patients with severely impaired kidney function, heart failure, acute myocardial infarction, or serious infections should not use this medication. Before and after examinations using contrast agents, interruption of this medication is required due to the risk of renal function deterioration and lactic acidosis, for a certain period around the tests. It is safer for women who are pregnant, potentially pregnant, or lactating not to take this medication. During treatment, be aware of the rare but potentially fatal metabolic condition called lactic acidosis; if symptoms such as muscle pain, weakness, difficulty breathing, or abdominal pain arise, promptly inform medical personnel. This medication can cause hypoglycemia, so particularly when taken in conjunction with insulin or sulfonylureas, blood sugar levels should be regularly checked, and symptoms of hypoglycemia should be closely monitored. Elderly patients or those with reduced kidney function may need to undergo regular kidney function tests, and dose adjustments may be necessary. Alcohol consumption may increase the risk of lactic acidosis; therefore, avoid excessive drinking during treatment. If surgery is planned, discontinue use of this medication 48 hours prior to the procedure, and restart only after normal oral intake is achieved and kidney function is confirmed. During treatment, regular blood tests, kidney function tests, and monitoring of vitamin B12 levels are necessary; consult a physician immediately if abnormal symptoms occur. There may be drug interactions; if taking other medications, it is essential to inform healthcare professionals, especially when combining with drugs affecting renal excretion.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, Stevens-Johnson syndrome, skin rash, skin desquamation, pain in mucous membranes of mouth/eyes, severe skin reactions, difficulty breathing, respiratory distress, asthma attack, acute pancreatitis, liver abnormalities (jaundice), acute kidney failure, worsening of renal function due to acute kidney failure, severe edema, edema accompanied by increased blood pressure, severe headache, seizures, confusion, visual disturbances

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infections
• pharyngitis
• headache
• hypoglycemia
• constipation
• indigestion

This medication should be stored in a tightly sealed container that does not allow air in, at room temperature between 1 and 30 degrees Celsius. This storage method helps to maintain the medication's effectiveness over time.

Appearance

Pink, oval-shaped film-coated tablets

Package unit

30 tablets/bottle