Medication info
Nexial-D Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Nexial-D Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.25mg / 1 tablet
Manufacturer / importer
제이더블유신약(주)
Appearance
Pale pink round film-coated tablet
Packaging
28 tablets/box [(14 tablets/PTP x 2)]
Approval status
Active

MFDS item code 201507477 · Approved 2015.10.30 · Insurance code 644102810

Summary

Main use
Treatment of gastroesophageal reflux disease (reflux esophagitis, symptoms) and treatment of Helicobacter pylori-positive peptic ulcers, relief of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs, treatment and prevention of gastric and duodenal ulcers
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of reflux esophagitis: 40 mg once daily for 4 weeks If not treated or symptoms persist, additional 4 weeks of treatment - Long-term maintenance therapy for preventing relapse: 20 mg once daily - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily,
Children's dosage
Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) Treatment of reflux esophagitis: 40 mg once daily for 4 weeks If not treated or symptoms persist, additional 4 weeks of treatment

Ingredients

Manufacturer
제이더블유신약(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (reflux esophagitis, symptoms) and treatment of Helicobacter pylori-positive peptic ulcers, relief of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs, treatment and prevention of gastric and duodenal ulcers

  • Gastroesophageal reflux disease
  • reflux esophagitis
  • esophagitis
  • Helicobacter pylori-positive duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease and reflux esophagitis. It is also used for long-term maintenance therapy to prevent recurrence in patients with esophagitis. Additionally, it is effective in treating and preventing recurrence of duodenal ulcers and peptic ulcers in patients with Helicobacter pylori infection. It is used for the treatment and prevention of ulcers related to gastrointestinal symptoms caused by nonsteroidal anti-inflammatory drugs. Furthermore, it is applied for maintenance therapy for Zollinger-Ellison syndrome and prevention of rebleeding from gastric or duodenal ulcers. Overall, it improves symptom relief and recurrence prevention of various digestive diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of reflux esophagitis: 40 mg once daily for 4 weeks If not treated or symptoms persist, additional 4 weeks of treatment - Long-term maintenance therapy for preventing relapse: 20 mg once daily - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily,

Children's dosage

Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) Treatment of reflux esophagitis: 40 mg once daily for 4 weeks If not treated or symptoms persist, additional 4 weeks of treatment

Precautions

This medication should not be used in patients allergic to specific ingredients or benzimidazole compounds. Caution is needed when administering to patients with allergies to penicillin or macrolide antibiotics in combination therapy. This medication should not be administered to breastfeeding women, patients with a history of myocardial infarction, or patients taking certain antiviral medications. The medication contains a dye called Yellow No. 5, and individuals allergic to this ingredient should use it cautiously. Rarely, various side effects such as blood abnormalities, allergic reactions, hypomagnesemia, headache, dizziness, abdominal pain, skin rash may occur; if any symptoms occur, consult a doctor immediately. Long-term use requires regular testing to monitor for abnormalities. This medication suppresses gastric acid secretion and may increase the risk of bacterial overgrowth in the stomach; if diarrhea persists, inform the healthcare professional. Patients with osteoporosis or those on long-term treatment may have an increased risk of fractures and may require bone density testing. This medication may interact with other drugs, especially anticoagulants, antiviral medications, and anticonvulsants, so it is essential to inform healthcare providers if you are on these medications. Use during pregnancy is limited, and it is recommended not to take this medication while breastfeeding. In case of overdose, there is no specific antidote; seek appropriate treatment immediately at a medical institution, and keep it out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, shock, jaundice, hepatitis, liver failure, encephalopathy, erythema multiforme, mucosal membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, Clostridium difficile-associated diarrhea, severe allergic reactions, severe skin adverse reactions, severe swelling or edema

Mild side effects

Headache, dizziness, sensation abnormality, drowsiness, taste disturbance, blurred vision, vertigo, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, candidiasis in the gastrointestinal tract, elevated liver enzymes, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, abdominal bloating,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is important to maintain the storage temperature between 1 to 30 degrees Celsius. Avoid storing in extremely hot or cold places.

Appearance and packaging

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP x 2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.