Celecox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or take 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or administer 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day onward, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks daily, so consultation with a physician or pharmacist is essential. It may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke; hence it should be used at the lowest effective dose for the shortest duration possible, and any cardiovascular symptoms should be reported to a healthcare professional immediately. This medication can cause serious adverse reactions such as gastrointestinal perforation, ulcers, and bleeding, particularly in elderly patients or those with a history of gastrointestinal disorders. It should not be administered to patients with specific allergic reactions, severe liver or kidney impairment, active peptic ulcer, heart failure, pregnant or breastfeeding women. Patients with liver or kidney issues, as well as histories of asthma, hypertension, heart failure, or diabetes should use this medication cautiously, with regular monitoring required during treatment. This medication may interact with various drugs; therefore, if you are taking other medications, you must inform your physician or pharmacist. Women who are pregnant or may become pregnant should not take this medication, and breastfeeding women are also advised to avoid it. Safety and efficacy in children and adolescents have not been established, hence it is not recommended for individuals under 18 years of age. Elderly patients may have reduced kidney, liver, and heart functions; thus, dose adjustments and careful observation are necessary. Dizziness or drowsiness may occur while taking this medication, so it is advisable to avoid driving or operating machinery. This medication is not a substitute for aspirin in the prevention of cardiovascular disease, and concomitant use with aspirin may increase the risk of gastrointestinal side effects. Regular blood tests and liver and kidney function tests should be performed during prolonged use to monitor for abnormalities, and should any abnormal symptoms arise, discontinue immediately and consult a healthcare professional. Overdose of this medication can result in symptoms such as lethargy, drowsiness, nausea, vomiting, and gastrointestinal bleeding; immediate medical assistance should be sought. Keep out of reach of children and do not transfer to another container for safety.

Gastrointestinal hemorrhage, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, hyposmia, ageusia, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute kidney injury, hyponatremia, menstrual disorders, chest pain, vasculitis, nosebleeds, speech disorders, pneumonia, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, hepatitis, jaundice, liver failure, increased blood sodium, increased blood potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, gustatory disturbances, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, kidney dysfunction, acute kidney injury, interstitial nephritis, anaphylactic reactions, hallucinations, intracranial hemorrhage, aseptic meningitis, ageusia, hyposmia, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute kidney injury, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microleak glomerulonephritis, female infertility

Store this medication in a tightly sealed container to prevent air ingress and at room temperature between 15 to 30 degrees Celsius. This storage will help maintain the medication's effectiveness and prevent degradation.

Appearance

A capsule filled with white to pale yellow powder, with an upper and lower white part.

Package unit

30 capsules/bottle, 100 capsules/bottle