Losarzen Plus Tablets

Adult dose

The usual dose of this medication is Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg, one tablet once a day. Doses exceeding Losartan potassium 100 mg/Hydrochlorothiazide 25 mg per day are not preferred. - For patients whose blood pressure is not controlled with monotherapy using Losartan or Hydrochlorothiazide: start treatment with Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg, one tablet once a day.

Child dose

There is no experience of use in children and adolescents (under 18 years of age), so this combination should not be administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients allergic to any ingredients in this medication, those with certain kidney and liver dysfunctions, and women of childbearing potential should not take this drug. Patients with low blood pressure, kidney abnormalities, electrolyte imbalances, elderly patients, and those with a history of certain skin cancers should use this medication cautiously. During usage, it is necessary to regularly monitor electrolyte levels in the blood and kidney function to ensure there are no abnormalities. This medication lowers blood pressure, so dizziness or drowsiness may occur at the beginning of treatment or when changing doses, which requires caution while driving or operating machinery. It may interact with other medications; therefore, patients should inform their doctor or pharmacist of all medications they are currently taking, especially potassium supplements or certain diuretics. This medication may be sensitive to sunlight, so precautions should be taken to protect against UV light, and if any unusual skin reactions occur, medical consultation should be sought immediately. Keep out of reach of children and store in the original container to prevent misuse or degradation of quality.

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of lips and eyelids and facial rash), chest tightness, difficulty breathing, angioedema (could cause airway obstruction from laryngeal/glottic swelling, swelling of the face/lips/pharynx/tongue), cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, yellowing of the skin or eyes (jaundice), severe lethargy, skin and mucous membrane syndrome (Stevens-Johnson syndrome)

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a container that does not allow light to enter. It should also be stored at room temperature between 1 and 30 degrees Celsius, avoiding very hot or cold places. This will help maintain the medication's effectiveness over time.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle