Serenojik Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication must be consulted with a doctor or pharmacist if taken by individuals who frequently consume more than 3 alcoholic drinks per day. Taking it with alcohol may increase the risk of gastrointestinal bleeding. This medication can increase the risk of myocardial infarction or stroke in individuals with heart or vascular issues or those at risk of cardiovascular disease, so it should be used at the lowest possible dose and for the shortest duration. Seek immediate medical attention if cardiovascular symptoms occur. In terms of gastrointestinal concerns, severe issues such as gastric ulcers, gastrointestinal bleeding, or perforation may arise, especially in older adults or those with a history of gastrointestinal diseases. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis occur, visit the hospital immediately. This medication should not be used in individuals with certain allergic reactions, severely impaired liver or kidney function, active gastric ulcers or inflammatory bowel disease, a history of heart failure or cardiovascular disease, or in pregnant or breastfeeding women. Individuals with weak liver or kidney functions, hypertension, asthma, heart failure, fluid retention, older adults, or diabetes should exercise caution while using this medication and require regular health status checks. Various side effects such as headaches, dizziness, indigestion, vomiting, skin rashes, edema, or hypertension may occur during treatment, so if symptoms worsen or unusual reactions are suspected, consult medical personnel immediately. This medication is metabolized in the liver, and drug interactions may occur when taken with other medications that can affect liver function, so inform medical personnel about other medications being taken. Pregnant women or those planning to become pregnant should consult a doctor before taking this medication, and breastfeeding mothers may need to avoid it or stop breastfeeding. This medication has not established its safety and efficacy in children and adolescents under 18 years, so it is recommended not to use it in this population. Older adults are likely to have reduced kidney, liver, and heart function, so careful monitoring and management is needed while taking this medication. Regular blood tests, liver function tests, and kidney function tests should be conducted to check for any abnormalities, and if any signs are detected, treatment should be discontinued immediately and a doctor consulted. In the case of an overdose, symptoms such as nausea, vomiting, drowsiness, and lethargy may appear, and appropriate treatment should be sought immediately at a medical institution. This medication should be stored out of reach of children and should not be transferred to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, damage, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in regions such as the back, muscle rigidity, reduced hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, chest pain, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, pneumonia, shortness of breath, hearing loss, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized rash with pustules, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, female infertility

This medication should be stored in a sealed container to prevent air and moisture from entering, and it is best kept in a cool place between 15 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness over time.

Appearance

White capsule filled with a white to light yellow powder

Package unit

30 Capsules/Bottle, 100 Capsules/Bottle