Hyalton Injection (Sodium Hyaluronate)

Adult administration

Typically, for adults, inject 1 vial once a week for 3 consecutive weeks into the knee joint or shoulder joint, but the number of injections should be adjusted appropriately depending on the symptoms.

This medication should not be used in patients who have had an allergy to any of its components. Additionally, it should be used with caution in patients who have had allergies to other medications or who have liver function problems or a history of liver disease. Since this drug is injected directly into the joint, it should be administered carefully in patients with skin diseases or infections at the injection site. While using, severe allergic reactions, such as shock, may occur; if symptoms appear, the administration should be stopped immediately, and appropriate treatment should be sought. Moreover, swelling around the face or eyes, rash, and itching may occur, and if such symptoms arise, use of the drug should be discontinued. There may be temporary pain, swelling, warmth, and pressure in the injected joint area, and rarely, symptoms of fluid accumulation may occur. Nausea, vomiting, and fever may also occur occasionally. In patients with severe inflammatory arthritis, it is recommended to reduce inflammation before using this medication. After injection, it is advisable to take measures to stabilize the injection site. Care should be taken to ensure that the drug is injected accurately into the joint without leaking outside the joint. Strict sterile conditions must be maintained during injection, and the number of injections should be limited to 3 if symptoms do not improve. If there is fluid accumulation within the joint, it may be necessary to extract the fluid as needed. This medication is prohibited for intravascular use and is also not suitable for use in the eyes. It is recommended to use a needle size of 22-23 gauge. Also, caution should be exercised as the drug may precipitate when used with certain disinfectants. Women who are pregnant or may become pregnant should only use this medication cautiously when the benefits outweigh the risks, and lactating women should avoid administration. For children, safety has not been established, so it should only be used cautiously when necessary. Elderly patients may have impaired physical functions, so use should be undertaken with extra caution.

Serious side effects

• Shock symptoms
• urticaria
• severe swelling (edema)

Mild side effects

Hypersensitivity, edema (facial, eyelid, etc.), facial flushing, rash, urticaria, itching, pain (mainly transient pain after administration), swelling, fluid retention, erythema, warmth, local severe pressure sensation, nausea, vomiting, fever, localized pain, exacerbation of local inflammatory symptoms

This medication should be stored in a sealed container at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness and prevents deterioration.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial or plastic vial (pre-filled syringe) sealed with rubber stoppers at both ends.

Package unit

2.0mL/vial X 3 vials