Medication info

Dexiprin 400mg (Dexibuprofen)

Prescription medicationTabletOralApproval withdrawn
Ingredient · strength
Dexibuprofen D.C.›400mg / 1 tablet
Manufacturer / importer
Celltrion Pharmaceutical Co., Ltd.
Appearance
White oblong film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201507381 · Notified 2015.10.26

This product's status changed to Approval withdrawn on 2024.03.29. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of joint disorders (including arthritis), pain and inflammation after trauma or surgery, and adjunctive treatment of infections
Who takes it
Adults
Adult dose
○ Adults: Administer 400 mg of dexibuprofen orally 2~3 times daily. However, do not exceed 1,200 mg of dexibuprofen per day.

Ingredients

Manufacturer
Celltrion Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of joint disorders (including arthritis), pain and inflammation after trauma or surgery, and adjunctive treatment of infections

  • Chronic polyarthritis
  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • painful swelling
  • inflammation
  • pain
  • fever
View approved original text

This medication is effective for chronic inflammatory joint diseases such as chronic polyarthritis and rheumatoid arthritis. It also helps relieve pain and inflammation associated with osteoarthritis and ankylosing spondylitis. It is used to reduce painful swelling and inflammation that occur after trauma or surgery. Additionally, it can be used as an adjunct treatment for infections accompanied by inflammation, pain, and fever. Overall, it is used to alleviate and treat various symptoms related to joints and inflammation.

How to take

Adult dose

○ Adults: Administer 400 mg of dexibuprofen orally 2~3 times daily. However, do not exceed 1,200 mg of dexibuprofen per day.

Precautions

This drug may pose a risk of stomach bleeding if taken by individuals who regularly consume more than 3 drinks per day, so it is important to consult a doctor or pharmacist. This medication can affect the cardiovascular system and increase the risk of serious thrombotic reactions such as myocardial infarction and stroke, so individuals with cardiovascular diseases or risk factors should exercise caution. It can cause serious gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforation, so caution is especially needed for elderly individuals or those with a history of gastrointestinal diseases. It is safer not to take this drug in cases of gastrointestinal ulcers or bleeding, severe liver or kidney impairment, severe heart failure, hypertension, blood disorders, a history of asthma, etc. When taken with aspirin or other non-steroidal anti-inflammatory drugs, there is an increased risk of gastrointestinal bleeding, and the efficacy of this medication may be diminished, so concurrent use should be avoided. Pregnant individuals beyond 6 months of gestation should not take this medication due to potential effects on the fetus. Dizziness or fatigue may occur during the use of this medicine while driving or operating machinery, so caution is required. If breastfeeding, consider stopping nursing or the medication, as this drug may transfer into breast milk and cause adverse reactions in the baby. Long-term high-dose use may cause headaches, so caution is required. While taking this medication, regular check-ups for liver function, kidney function, blood tests, etc., are necessary to check for any abnormalities. If symptoms of severe allergic reactions, skin rashes, difficulty breathing, severe gastrointestinal problems, or blood disorders occur, discontinue use immediately and consult a doctor. This medication may specifically affect fetal renal function after 20 weeks of pregnancy, so if necessary, it should only be used at the minimum dose and for the shortest duration, with regular monitoring of amniotic conditions. In case of overdose, even without symptoms, seek medical attention immediately, and steps for gastric lavage or dilution should be taken as soon as possible. This medication should be stored out of reach of children, protected from direct sunlight, and kept in a cool, dry place.

Side effects

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, gastrointestinal or intestinal bleeding, ulcers, perforation, dyspepsia, abdominal bloating, heartburn, upper abdominal pain, diarrhea, constipation, loss of appetite, nausea, vomiting, abdominal pain, upper gastrointestinal discomfort, esophagitis, esophageal stenosis, diverticulitis exacerbation, nonspecific hemorrhagic colitis, ulcerative colitis, Crohn's disease, peptic ulcer gastrointestinal bleeding, perforation, hematochezia, gastritis, pancreatitis, thirst, stomatitis, erythema multiforme, systemic lupus erythematosus, hair loss, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, eosinophilia, drug rash with systemic symptoms, rash, urticaria, pruritus, purpura, asthma attack, eczema, anaphylactic reaction, photosensitivity reaction, jaundice, elevated ALT, elevated AST, elevated ALP, abnormal liver function, hepatitis, rhinitis, bronchospasm, acute pneumonia, neglect, cancer invasion, visual impairment, hearing loss, tinnitus, taste disturbance, fatigue, drowsiness, headache, dizziness, anxiety, restlessness, confusion, depression, aseptic meningitis, psychiatric symptoms, agitation, excitement, disorientation, reversible toxic encephalopathy, hypotension, hypertension, palpitations, acute renal failure, oliguria, hematuria, increased urinary protein, increased BUN, elevated serum creatinine, hyperkalemia, decreased urine output, generalized edema, shortness of breath, lethargy, renal papillary necrosis, nephrotic syndrome, interstitial nephritis, peripheral edema, acute pulmonary edema, fluid retention, reduced reproductive capacity in women, periorbital edema, malaise, fever, epistaxis, worsening inflammation, crying, facial edema, dyspepsia, itching, anaphylactic shock, rash, headache

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.