Medication info
Yesome Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Yesome Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.3mg / 1 tablet
Manufacturer / importer
(주)한국파비스제약
Appearance
Pale pink round film-coated tablet
Packaging
28 tablets (14 tablets/PTP) x 2
Approval status
Active

MFDS item code 201507371 · Approved 2015.10.26 · Insurance code 621802760

Summary

Main use
Treatment and prevention of recurrence of gastroesophageal reflux disease (such as erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcers, and relief of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid, such as water, and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If not treated or symptoms persist, an additional 4 weeks of treatment. - Long-term maintenance therapy for prevention of recurrence: Administer 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: Administer once daily.
Children's dosage
Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If not treated or symptoms persist, an additional 4 weeks of treatment.

Ingredients

Manufacturer
(주)한국파비스제약

Efficacy & effects

Treatment and prevention of recurrence of gastroesophageal reflux disease (such as erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcers, and relief of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs.

  • Erosive esophagitis
  • esophagitis
  • symptoms of gastroesophageal reflux disease
  • Helicobacter pylori positive duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • rebleeding from gastric ulcers
View approved original text

This medication is used as maintenance therapy for the treatment and prevention of recurrence of erosive esophagitis related to gastroesophageal reflux disease. It is also utilized in antibiotic combination therapy for the treatment and prevention of recurrence of duodenal ulcers and peptic ulcers caused by Helicobacter pylori infection. Furthermore, it is effective not only for treating upper gastrointestinal symptoms that arise from the use of non-steroidal anti-inflammatory drugs but also for treating gastric ulcers and preventing ulcers in patients receiving long-term non-steroidal anti-inflammatory drug treatment. Additionally, it is used for the treatment of Zollinger-Ellison syndrome and for preventive maintenance therapy against rebleeding in gastric and duodenal ulcers. Collectively, it improves various ulcer and inflammatory symptoms related to gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid, such as water, and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If not treated or symptoms persist, an additional 4 weeks of treatment. - Long-term maintenance therapy for prevention of recurrence: Administer 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: Administer once daily.

Children's dosage

Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If not treated or symptoms persist, an additional 4 weeks of treatment.

Precautions

This medication should not be administered to certain patients. Patients with a history of allergy or hypersensitivity to this drug or its components should not use it. Additionally, patients taking certain antibiotics or antiviral agents, nursing mothers, and patients with a history of myocardial infarction should not use this medication. This medication contains the dye Yellow No. 4, and patients allergic or sensitive to this ingredient should use it carefully. Various adverse reactions may occur with this medication. Gastrointestinal symptoms such as headaches, abdominal pain, diarrhea, nausea, and vomiting are common, and occasionally neurological symptoms such as insomnia, dizziness, and mental confusion may also occur. Rarely, serious side effects such as blood abnormalities, liver function abnormalities, skin rashes, and myalgia have been reported. Particularly, hypomagnesemia may occur, so magnesium levels should be checked regularly if used for a long time. This medication suppresses stomach acid, which may slightly increase the risk of bacterial infections in the gastrointestinal tract. Additionally, long-term high-dose use may increase the risk of fractures, so caution is needed for patients with osteoporosis. This medication may interact with other drugs, so particularly when used in combination with anticoagulants, antibiotics, antiviral agents, and anticonvulsants, a consultation with a doctor is advised. Data regarding use during pregnancy is limited, so it should be administered cautiously to pregnant women, and it is recommended not to use this medication while breastfeeding. In cases of overdose, there is no specific antidote, and treatment should be symptomatic, as this medication is not removed by dialysis. Lastly, this medication should be kept out of reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • severe swelling (angioedema)
  • chest tightness
  • difficulty breathing
  • cold sweat
  • paleness
  • fever
  • angioedema
  • anaphylactic reactions/shock
  • angioedema
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  • urticaria
  • yellowing of the skin or eyes (jaundice)
  • hepatitis
  • liver failure
  • sudden and severe headache
  • seizures
  • confusion
  • visual disturbances
  • paralysis
  • significant reduction in urine output
  • severe swelling throughout the body
  • accompanied by elevated blood pressure
  • Stevens-Johnson syndrome.

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, arthralgia, myalgia, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain, retrosternal pain, facial swelling, facial flushing, fatigue, fever.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, at room temperature between 1 to 30 degrees Celsius. This helps maintain the medication's efficacy and safety.

Appearance and packaging

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets (14 tablets/PTP) x 2

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.