Esomeprazole Magnesium 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not satisfactorily treated or if symptoms continue, extend for another 4 weeks. - Maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily.

Children's dosage

Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. Extend for an additional 4 weeks if not satisfactorily treated or if symptoms persist.

This medication should not be given to certain patients. For example, patients who are allergic to this drug or any of its components or have experienced such reactions in the past, those allergic to penicillin or macrolide antibiotics, patients currently taking certain cardiac medications, those with a history of heart disease, and breastfeeding women should avoid taking this medication. This drug can cause various side effects. Common symptoms include headache, abdominal pain, diarrhea, constipation, and drowsiness, while rare but serious side effects such as blood disorders, severe allergic reactions, liver dysfunction, skin rashes, myalgia, and nephritis have also been reported. If muscle pain or weakness occurs, it is important to consult a healthcare provider immediately. Long-term use of this medication may lower magnesium levels in the blood, thus regular monitoring of magnesium levels is required, and supplementation should be made if necessary. Additionally, this medication can lower gastric acidity, potentially increasing bacterial growth in the gastrointestinal tract, which may heighten the risk of infection. This medication may interact with other drugs, so be sure to inform a healthcare provider about any medications currently being taken. Caution is especially needed when combined with anticoagulants, antiviral drugs, certain antibiotics, anticonvulsants, and immunosuppressants. Pregnant women should carefully consider using this medication, and it is safer not to take it while breastfeeding. In the case of overdose, there is no specific antidote, so treatment should be symptomatic, and the medication should be stored in a safe place out of the reach of children. Furthermore, transferring the medication to other containers is not recommended as it may compromise quality.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, hypomagnesemia, mental confusion, taste disorder, jaundice, hepatitis, liver failure, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), erythema multiforme, rhabdomyolysis, severe skin adverse reactions (SCAR), severe allergic reactions, severe...

Mild side effects

• Headache
• dizziness
• sensory disturbances
• drowsiness
• taste disorder
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication must be stored in a tightly closed container to protect it from air and moisture. It is also safe to store it at room temperature, between 1 and 30 degrees Celsius, not in excessively hot or cold places.

Appearance

Pink, round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2)