Busomezol Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: take 40 mg once daily for 4 weeks. An additional 4 weeks may be taken if needed. - Maintenance therapy to prevent recurrence: take 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: take 20 mg once daily. If symptoms are not controlled after 4 weeks, further medical advice is necessary.

Children's dosage

For adolescents aged 12 years and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: take 40 mg once daily for 4 weeks. An additional 4 weeks may be taken if needed. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: take 20 mg once daily

This medicine should not be used by patients who have experienced allergic reactions or hypersensitivity to certain ingredients or drugs. In particular, patients who are allergic to penicillin or macrolide antibiotics and those taking certain heart-related medications should avoid administration. Nursing women and patients with a history of myocardial infarction should also not use this medication. This medication contains the dye Yellow No. 5, so patients with allergic reactions to this ingredient should use it with caution. While using, various side effects such as headache, dizziness, indigestion, and skin rash may occur, so if any abnormal symptoms appear, it is essential to consult a medical professional immediately. Long-term use requires regular health check-ups, particularly periodic monitoring of magnesium levels and liver function. This medication suppresses gastric acid secretion, which may promote the growth of bacteria in the stomach; thus, patients should inform their healthcare provider if symptoms like diarrhea persist. Furthermore, patients at risk for osteoporosis or fractures should carefully manage bone health when using high doses for extended periods. Since there are many drug interactions, it is crucial to inform physicians or pharmacists of any medications being taken, and special caution is advised when taken with certain antiviral or anticoagulant drugs. Safety data regarding use during pregnancy is limited, hence women who are pregnant or planning to become pregnant should consult a specialist before taking this medication. In cases of nursing, it is advised not to use this medication as it may be passed into breast milk. There are no specific antidotes for overdose, so treatment should be symptomatic and require general management; it should be stored in a safe place out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, hypomagnesemia, hepatitis, liver failure, jaundice, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, rhabdomyolysis, sudden and very severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, difficulty breathing

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disorder, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, facial edema, flushing, fatigue, fever, influenza

This medication may be sensitive to air and moisture, therefore, it should be stored in a tightly sealed container. Also, it is recommended to keep the drug at room temperature between 1 to 30 degrees Celsius, away from extremes in heat or cold.

Appearance

Light pink round film-coated tablet

Package unit

28 tablets/PTP