DuoNonjeong 10/5 mg

Adult dose

This medication is taken once daily, regardless of meals. The recommended starting dose is 10/5 mg daily. The dosage range is between 10/5 mg and 10/20 mg daily. For patients requiring further reduction in LDL cholesterol, dosage can be adjusted. After initiation of treatment or adjustment of dosage, lipid levels should be checked at intervals of at least 4 weeks, and the dose can be increased up to a maximum of 10/20 mg daily.

This medication can affect the muscles, so if muscle pain or weakness occurs, it should be reported to a physician immediately. Particularly in cases of acute infection, major surgery, severe trauma, or metabolic disorders, the use of this medication should be discontinued or temporarily paused. Patients who are allergic to any ingredient in this medication or those with severely impaired liver or kidney function should not take this medication. Women who are pregnant or may become pregnant, as well as nursing mothers, should not use this medication. Additionally, those with a history of muscle disease or certain medications may have an increased risk of muscle problems, hence caution is advised. This medication contains lactose, so patients with a genetic problem like lactose intolerance should not take it. Patients with a history of alcohol dependence or liver disease should use this medication cautiously, and it is recommended not to administer it in cases of severely impaired liver function. Elderly patients or those with impaired kidney function are also at higher risk for muscle problems, hence careful monitoring is necessary. Regular monitoring of liver function and muscle condition is required during the intake of this medication, and if liver enzyme levels rise significantly, the medication may need to be discontinued. When combined with other medications, interactions can alter drug concentrations, so it is essential to consult a physician or pharmacist. Taking this medication during pregnancy can harm the fetus; if pregnancy is confirmed, the medication should be discontinued immediately and a physician consulted. It is also advisable not to take this medication while nursing. Safety in children and adolescents has not been adequately established, thus its use is not recommended. In cases of overdose, there is no specific antidote; treatment should be symptom-based, and liver and muscle monitoring should be conducted.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucous membranes, breathlessness or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, urination issues

Mild side effects

• Nasopharyngitis
• dyspepsia
• headache
• dizziness
• constipation
• nausea
• abdominal pain
• dry mouth
• elevated liver enzymes
• myalgia

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Pink rectangular film-coated tablet

Package unit

30 tablets (10 tablets/PTP × 3), 30 tablets/bottle, 100 tablets/bottle