Medication info
Crezet Tablet 10/10 mg (Ezetimibe, Rosuvastatin)

Crezet Tablet 10/10 mg (Ezetimibe, Rosuvastatin)

Prescription medicationTablet경구
Ingredient · strength
Rosuvastatin Calcium›10.4mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)대웅제약
Appearance
Yellow rectangular film-coated tablet
Packaging
30 tablets (10 tablets/PTP x 3), 30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201506786 · Approved 2015.09.24 · Insurance code 641606130

Summary

Main use
Lipid control for hypercholesterolemia (primary, mixed) and risk reduction of atherosclerotic vascular diseases.
Who takes it
Adults
Adult dose
This medication is administered once daily, regardless of meals. The dosage range is between 10/5mg and 10/20mg daily, with an initial dose of 10/5mg recommended. For patients requiring more significant LDL cholesterol reduction, the dosage may be adjusted. After initiating treatment or adjusting the dosage, check blood lipid levels at intervals of at least 4 weeks before adjusting the dosage again. The maximum daily dosage is

Ingredients

Manufacturer
(주)대웅제약

Efficacy & effects

Lipid control for hypercholesterolemia (primary, mixed) and risk reduction of atherosclerotic vascular diseases.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated apolipoprotein B
  • elevated triglycerides
  • elevated non-HDL cholesterol
  • increased risk of atherosclerotic vascular diseases due to hypercholesterolemia.
View approved original text

This medication helps improve cholesterol and triglyceride levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It specifically lowers elevated total cholesterol, LDL cholesterol, apolipoprotein B, triglycerides, and non-HDL cholesterol levels while increasing levels of HDL cholesterol, commonly known as good cholesterol. This treatment is carried out alongside dietary modifications and is used as an adjunct when monotherapy is insufficient. It is crucial to identify other causes of dyslipidemia before treatment and address them as needed. Additionally, lipid level testing should be conducted to monitor treatment response, and it can be administered to patients with acute cardiovascular events at the appropriate time. This medication is used to reduce cardiovascular risks due to hypercholesterolemia and improve lipid levels.

How to take

Adult dose

This medication is administered once daily, regardless of meals. The dosage range is between 10/5mg and 10/20mg daily, with an initial dose of 10/5mg recommended. For patients requiring more significant LDL cholesterol reduction, the dosage may be adjusted. After initiating treatment or adjusting the dosage, check blood lipid levels at intervals of at least 4 weeks before adjusting the dosage again. The maximum daily dosage is

Precautions

This medication has been reported to cause rare side effects related to muscle damage, including rhabdomyolysis, so immediate consultation with a physician is necessary if severe muscle pain or weakness occurs. It may affect liver function, therefore, patients with liver disease or abnormally high liver enzyme levels should not use it. Patients with muscle disorders or severely impaired kidney function, pregnant or potentially pregnant women, and nursing mothers should not take this medication. This medication should not be administered to patients with specific genetic lactose intolerance and should be avoided in cases of drug allergy. Patients with a history of alcohol dependence or liver disease, the elderly, and those with risk factors for myopathy should use this medication cautiously. During treatment, if symptoms such as muscle pain, cramps, weakness, fatigue, or fever appear, inform healthcare professionals immediately, and blood tests may be necessary to check for muscle damage. If liver enzyme levels rise or symptoms of liver damage occur, medication should be discontinued, and follow a physician’s instructions. This medication may interact with other drugs, so inform healthcare professionals if taking other medications, especially anticoagulants, fibrates, cyclosporine, and certain antibiotics and antifungals. Pregnant women or those planning pregnancy should not use this medication, and women of childbearing age should ensure appropriate contraception while on the medication. Safety and effectiveness in children have not been established, so it is not recommended for pediatric use. In cases of overdose, there is no specific antidote, so symptomatic treatment and supportive care should be administered, and liver and muscle-related tests should be performed. Store the medication out of reach of children and avoid transferring it to other containers. Be cautious, as symptoms such as dizziness may arise during driving or operating machinery. If severe skin rash, swelling, or difficulty breathing occurs while taking this medication, inform healthcare professionals immediately.

Side effects and when to seek care immediately

Serious side effects

Urticaria, swelling, chest tightness, cold sweat, difficulty breathing, pallor, severe rash accompanied by high fever, blistering, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output,

Mild side effects

  • Nasopharyngitis
  • dyspepsia
  • headache
  • dizziness
  • muscle pain
  • edema
  • dry mouth
  • elevated liver enzymes
  • pruritus
  • increased blood sugar
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  • elevated serum lactate dehydrogenase
  • increased serum creatinine
  • weakness
  • sensory abnormality
  • nausea
  • abdominal pain
  • diarrhea
  • loss of appetite
  • abdominal bloating
  • syncope
  • generalized pain
  • muscle cramps
  • gout
  • erectile dysfunction
  • joint pain
  • fatigue
  • itching
  • dermatitis
  • skin burning sensation
  • alopecia
  • skin disorders
  • cough
  • phlegm
  • runny nose

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

Yellow rectangular film-coated tablet

Package unit

30 tablets (10 tablets/PTP x 3), 30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.