CANTACAN 8 mg (Candesartan Cilexetil)

Adult dose

For essential hypertension, the recommended initial and maintenance doses are 8 to 16 mg of Candesartan Cilexetil administered orally once daily. If blood pressure is not adequately controlled after 4 weeks of treatment at 16 mg daily, the dosage may be increased to a maximum of 32 mg once daily. For patients with reduced intravascular effective blood volume and those with kidney impairment, the initial dose is 4 mg; for patients with liver impairment, the initial dose is 2 mg once daily.

Child dose

Safety and efficacy in children and adolescents under 18 years of age have not been established.

This medication may cause serious harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so treatment must be discontinued immediately if pregnancy is confirmed. This medication should not be administered to women who are allergic to this drug or its components, are pregnant or breastfeeding, have severe liver disease or biliary obstruction, have a history of angioedema, certain hereditary angioedema conditions, or primary hyperaldosteronism. Patients with lactose intolerance or certain genetic metabolic disorders should not take this drug. Careful administration is required in elderly patients, those with hyperkalemia, mild to moderate liver impairment, certain valvular heart diseases or obstructive cardiomyopathy, ischemic heart disease, cerebrovascular disorders, renal artery stenosis, those with reduced intravascular effective blood volume, diminished renal function, patients who have recently received a kidney transplant, and those under 18 years of age. Common side effects include dizziness, back pain, and respiratory infections, and serious side effects, though rare, may include leukopenia, hepatic abnormalities, angioedema, myalgia, and worsening renal function, necessitating immediate consultation with a physician if symptoms occur. In heart failure patients, hypotension, hyperkalemia, and renal function impairment may occur, so regular monitoring of serum potassium and creatinine levels is important. This medication has a blood pressure-lowering effect; therefore, caution is required as dizziness or fainting may occur if blood pressure drops too low, especially in patients undergoing hemodialysis or on strict salt restrictions or diuretics, necessitating careful dose adjustments and close observation. This medication may enhance the effects of other antihypertensive agents, so patients should notify their physician if they are taking other medications and take care when using them together. When combined with potassium-sparing diuretics or potassium supplements, serum potassium levels may rise to dangerous levels, requiring regular blood tests for monitoring. Pregnant women or women planning to become pregnant should not use this medication, and breastfeeding mothers are advised to avoid it as well. Safety and effectiveness in children and adolescents have not been established, so use is not recommended. In case of overdose, symptoms such as hypotension, dizziness, and rapid heartbeat may occur, requiring immediate medical attention. This medication should be stored out of reach of children, and transfer to other containers may affect its quality, so it is advisable to keep it in its original packaging. Caution should be exercised when driving or operating machinery, as dizziness or lethargy may occur due to medication intake.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, severe cutaneous adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, yellowing of the skin or eyes (jaundice), profound fatigue, liver abnormalities (jaundice), sudden changes

Mild side effects

• Dizziness
• back pain
• respiratory infections
• fatigue
• peripheral edema
• chest pain
• headache
• bronchitis
• cough
• sinusitis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to preserve the efficacy and safety of the drug.

Appearance

Pink, double-convex, round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle