Neo-Mezol Tablet 20mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, continue for another 4 weeks. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily.

Children's dosage

Adolescents aged 12 years and older - Treatment of gastroesophageal reflux disease Erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, continue for another 4 weeks. - Esophagitis

This drug should not be used in patients with hypersensitivity to certain components or benzimidazole derivatives or those with a history of such experiences. In addition, patients with hypersensitivity to penicillin or macrolide antibiotics should not receive this medication when combined with other antibiotics for the eradication of Helicobacter pylori. It should also be avoided in patients taking cardiac-related medications or certain antiviral agents, and in women who are breastfeeding or have a history of myocardial infarction. This drug contains a dye called Yellow No. 5, so patients with an allergy to this component should use it cautiously. During administration, various adverse reactions may occur, including headache, abdominal pain, diarrhea, rash, myalgia, and rarely serious blood abnormalities or liver dysfunction may occur. With long-term use, electrolyte abnormalities such as hypomagnesemia may occur, requiring regular tests. Also, this medication reduces gastric acidity, which may increase the risk of infections, so if diarrhea persists, it is important to consult a doctor immediately. There are significant drug interactions, so any concurrent medications must be discussed with healthcare providers, particularly when used with warfarin, methotrexate, or clopidogrel. Safety during pregnancy has not been fully confirmed; it should be used cautiously when necessary, and it is preferable not to administer it while breastfeeding. In case of overdose, there is no specific antidote, so treatment and general management will be based on symptoms. Store out of the reach of children and do not transfer to other containers for safety.

Serious side effects

• Severe allergic reactions such as urticaria, angioedema, anaphylaxis, shock, angioedema, urticaria, etc.
• Severe skin reactions including severe rash with high fever, blisters, desquamation, mucocutaneous syndromes (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms drug reaction (DRESS syndrome), etc.
• Shortness of breath or difficulty in breathing

Mild side effects

• Fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety
• confusion
• depression
• aggression
• hallucinations

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it should be kept at room temperature between 1 and 30 degrees Celsius. Avoid direct sunlight and high temperatures, and it is important to keep it out of the reach of children.

Appearance

Pale pink round film-coated tablet

Package unit

PTP - 28 tablets/box [28 tablets (14 tablets/Alu-Alu X 2)]