Metformin Citrate 50/500 mg

Adult dosage

This medication is generally taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal adverse reactions attributed to metformin. 1. Patients not currently treated with metformin: Start with this medication 50/500 mg taken twice daily, 1 tablet per dose, and it may be increased to 50/1000 mg taken twice daily, 1 tablet per dose. 2. Patients currently receiving metformin treatment

This medication is used for the treatment of diabetes and helps in controlling blood sugar. During treatment, serious allergic reactions may occur. If symptoms such as skin rash or difficulty breathing occur, it is essential to stop taking the medication immediately and consult a doctor. There is a risk of acute pancreatitis, an inflammation of the pancreas, so if symptoms such as abdominal pain, vomiting, or nausea occur, visit a hospital immediately. Patients with impaired kidney function, severe infections, or dehydration should not take this medication. It is also contraindicated in patients with severe heart diseases such as severe heart failure or acute myocardial infarction, as well as in pregnant or breastfeeding women. Care is required when there are irregular meals, vigorous exercise, or concomitant use with other medications, as side effects such as hypoglycemia or lactic acidosis may occur. This medication may cause side effects such as gastrointestinal disturbances, headaches, upper respiratory infections, and hypoglycemic symptoms may also be observed. When taken with other hypoglycemic agents, the risk of hypoglycemia may increase, so blood sugar levels should be monitored closely. Since this medication is excreted by the kidneys, regular kidney function tests must be performed, and dosage adjustment or discontinuation may be necessary in cases of decreased kidney function. Moreover, it may lower vitamin B12 levels, so it is advisable to check this through regular blood tests. Excessive alcohol consumption can increase the risk of side effects associated with this medication, so it is better to avoid drinking alcohol. Patients scheduled for surgery should stop taking this medication 48 hours prior to the surgery and can resume after surgery when kidney function has been confirmed to be normal. Elderly patients are at increased risk of decreased kidney function, so they should be especially cautious in their use and undergo regular kidney function tests. In case of overdose, seek immediate medical attention, as this medication can be partially removed through hemodialysis. During the use of this medication, regular checks for blood sugar, kidney function, and blood tests should be done, and if abnormal symptoms appear, consult a doctor immediately.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• rash
• Stevens-Johnson syndrome
• exfoliative skin disease
• severe rash accompanied by fever
• blisters
• skin peeling
• pain in oral/ocular mucosa

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air from entering and should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Pink oval film-coated tablet

Package unit

Company packaging unit