Abotase Soft Capsules (Dutasteride)

Adult dose

The recommended dose of this medicine is 1 capsule (0.5mg) once daily. Because exposure to the capsule contents may cause irritation of the oropharyngeal mucosa, swallow the capsule whole without chewing or opening it. This medicine may be taken with or without food. No dose adjustment is necessary in patients with renal impairment or in elderly patients. As there are no data on the administration of this medicine to patients with hepatic impairment, the recommended dose for these patients has not been established.

This medication can be absorbed through the skin, and women who are pregnant or may become pregnant should avoid direct contact with this medication. If a capsule breaks and the medication contacts the skin, it should be washed off immediately with soap and water. This medication should not be used in children under 18 years of age, and contact with broken capsules should also be avoided. Women, children under 18 years of age, and individuals allergic to this medication or similar components should not take this medication. Adult males planning to conceive should use this medication cautiously after consulting a doctor, as it may affect reproductive ability. Patients with difficulty in urinary drainage or severe reduction of urinary flow need to be careful while using this medication and should closely monitor for the occurrence of urinary retention symptoms. This medication should be administered with caution in patients with poor liver function. Moreover, patients taking medications that strongly inhibit certain drug metabolism enzymes (CYP3A4) should be cautious, as this medication may elevate blood concentration. Taking this medication may lead to sexual function-related side effects such as erectile dysfunction, decreased libido, and ejaculation disorders, and some patients may experience breast tenderness or enlargement. These side effects may persist after discontinuation of the medication, so it is important to consult a doctor if abnormal symptoms occur. This medication can lower blood PSA levels, so this should be considered when interpreting PSA levels for prostate cancer testing. If PSA levels rise again during treatment, it may raise suspicion of prostate cancer or insufficient drug effectiveness, necessitating regular testing. There is a prohibition period for blood donation with this medication, so one should not donate blood for at least 6 months after use. It is not known to affect driving or machine operation abilities. There is no specific antidote for overdose, so if symptoms appear, one should visit a medical institution immediately for appropriate treatment. Keep this medication out of the reach of children and make sure not to transfer it from its original container to another.

• erectile dysfunction
• decreased libido
• ejaculation disorder
• gynecomastia
• headache
• gastrointestinal discomfort and pain
• sexual dysfunction
• breast disorders
• dizziness
• rash

This medication should be stored in a tightly closed container to prevent air or moisture from entering and in a cool place below 30 degrees Celsius. Storing it this way can help maintain the medication's effectiveness for a longer period.

Appearance

Transparent yellow oval soft capsules containing colorless and transparent contents

Package unit

30 capsules (15 capsules/PTPX2), 30 capsules (10 capsules/PTPX3)