Omeprin Capsule (Omeprazole)

Adult dose

Ⅰ) Adults 1) Gastric ulcer: Administer omeprazole 20mg per dose orally once daily. Most ulcers may heal within 4 weeks, although the healing period may vary among patients. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, administration of 40mg per dose once daily generally results in healing within 8 weeks, although the healing period may vary among patients. Repeat treatment if the ulcer recurs. 2) Short-term treatment of duodenal ulcer: Administer 20mg per dose orally once daily. Most ulcers may heal within 2 weeks, although the healing period may vary among patients. If healing is not complete after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other medicines, administration of 40mg per dose once daily generally results in healing within 4 weeks, although the healing period may vary among patients. Repeat treatment if the ulcer recurs. 3) Reflux esophagitis: Administer 20mg per dose orally once daily. Most cases may heal within 4 weeks, although the healing period may vary among patients. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, administration of 40mg per dose once daily generally results in healing within 8 weeks, although the healing period may vary among patients. Repeat treatment if the condition recurs. 4) Zollinger-Ellison syndrome: The initial dose is 60mg per dose orally once daily. Continue treatment, adjusting the dose appropriately for each individual. More than 90% of patients respond to doses of 20 - 120mg per day. If more than 80mg per day is administered, divide the dose into 2 doses per day. 5) Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg per dose orally once daily. If the condition recurs, the dose may be increased to 40mg per dose once daily. 6) Combination therapy with antibiotics to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this medicine 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this medicine 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the therapeutic effect is insufficient, omeprazole monotherapy may be continued. 7) Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg per dose orally once daily. Treatment is generally possible with 2-4 weeks of use. 8) Treatment of gastric and duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg per dose orally once daily. Most cases may heal within 4 weeks, although the healing period may vary among patients. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 9) Maintenance prevention of gastric and duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID use in patients with a history of gastric or duodenal lesions who are receiving long-term NSAID treatment: Administer 20mg per dose orally once daily. * Swallow this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in patients allergic to its components. In patients with gastric ulcers, if there is a possibility of malignant tumors, symptom relief can delay diagnosis, requiring caution. Additionally, proton pump inhibitors like this should not be used in conjunction with certain antiviral agents, so combinations should be avoided. This medication should not be given to patients with congenital lactose metabolism disorders due to the lactose contained in it. Dosing should be adjusted or used cautiously in patients with impaired liver function or the elderly. Symptoms such as headache, drowsiness, dizziness, and rarely psychotic symptoms may occur. Since liver function can be affected, if there are abnormal liver enzyme levels, the use of this drug should be stopped. Common digestive system symptoms include diarrhea, nausea, abdominal pain, as well as skin symptoms such as rash or itching. Severe allergic reactions such as angioedema, fever, and anaphylactic shock can occur rarely as hypersensitivity reactions. Various side effects, including decreased blood cell counts, myalgia, gynecomastia, and visual disturbances, have been reported, so consultation with a physician is necessary if symptoms arise. Long-term use may increase the risk of fractures and hypomagnesemia, requiring regular check-ups. This medication may affect the absorption of other drugs by suppressing gastric acid secretion, so interaction with concomitant medications should be monitored. Women who are pregnant or may become pregnant should use this medication cautiously, and nursing mothers should either avoid administration or discontinue breastfeeding. The safety for children has not been sufficiently established, so caution is needed in their use. In case of overdose, symptoms such as vomiting, diarrhea, and headache may appear, but most are temporary, and severe outcomes have not been reported. It should be stored out of reach of children, and it is safer to keep it in its original container without transferring it to another container.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, lightheadedness, confusion, agitation, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, constipation, nausea, vomiting, abdominal pain, abdominal bloating, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, pruritus, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, fatigue, peripheral edema, increased sweating, cloudy vision, visual impairment, taste disorder, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized pustular psoriasis, eosinophilia, drug reactions with systemic symptoms, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp, hypocalcemia, hypokalemia

This medication may be sensitive to air and moisture, so it should be kept in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This will help to maintain the drug's efficacy and safety for a long time.

Appearance

A hard capsule with an upper reddish-brown part and a lower pink part filled with yellowish delayed-release granules.

Package unit

28 capsules/bottle, 100 capsules/bottle