Medication info
Celebrex 200 mg Capsule (Celecoxib)

Celebrex 200 mg Capsule (Celecoxib)

Prescription medicationHard capsuleOral
Ingredient · strength
Celecoxib›200mg / 1 tablet
Manufacturer / importer
Allico Pharmaceutical Co., Ltd.
Appearance
An opaque hard capsule that is white with yellowish stripes, containing a white to light yellow powder.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201505202 · Approved 2015.07.31 · Insurance code 656003920

Summary

Main use
Relief of arthritis (including osteoarthritis and rheumatoid arthritis), acute pain, and primary dysmenorrhea
Who takes it
Adults
Adult dose
The minimum recommended dose of this medicine should be adjusted for each patient and may be administered with or without food. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose twice daily. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Ingredients

Manufacturer
Allico Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of arthritis (including osteoarthritis and rheumatoid arthritis), acute pain, and primary dysmenorrhea

  • Symptoms of osteoarthritis
  • symptoms of degenerative joint disease
  • symptoms of rheumatoid arthritis
  • symptoms of ankylosing spondylitis
  • acute pain
  • primary dysmenorrhea
View approved original text

This medication is used to relieve symptoms and signs of joint diseases such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It also effectively reduces acute pain that may occur after surgery or dental extraction. Additionally, it helps alleviate pain caused by primary dysmenorrhea. This medication is used to improve various pain and inflammation symptoms, enhancing the quality of life for patients.

How to take

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered with or without food. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose twice daily. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Precautions

Patients who consume large amounts of alcohol daily should consult a doctor or pharmacist before taking this medication. Frequent consumption of alcohol with this medication may increase the risk of gastrointestinal bleeding. This medication may increase the risk of heart or vascular problems, so it should only be used at the lowest effective dose for the shortest duration. Even if there is no history of cardiovascular disease, if symptoms related to the heart appear, immediate medical attention should be sought. There is a risk of ulcers or bleeding in the stomach, so particular caution is required for individuals with a history of gastrointestinal disorders or the elderly. If symptoms such as epigastric pain, indigestion, black stools, or vomiting occur, immediate medical attention should be sought. Patients with an allergy to this medication or those with specific liver, kidney, or heart conditions should not take it. Women who are pregnant or may become pregnant, as well as breastfeeding women, should also avoid using this medication. Patients with impaired liver or kidney function, asthma, and hypertension need careful monitoring by a doctor while taking this medication. This medication may cause various side effects, including indigestion, headache, dizziness, skin rash, edema, hypertension, etc. If any adverse effects occur, consult a physician immediately. This medication can interact with other medications, so if you are taking any other drugs, you must inform your doctor or pharmacist. Particular caution is needed when taken together with antihypertensives, diuretics, anticoagulants, and antidepressants. Do not take this medication during pregnancy or breastfeeding, and women planning to become pregnant should consult a doctor before use. The safety and efficacy of this medication have not been established in pediatric patients aged 18 years and younger, so it is advisable not to use it in this age group. The elderly may have decreased liver and kidney function, so careful observation is necessary while taking this medication. Regular blood tests and liver and kidney function tests should be conducted to ensure there are no abnormalities during treatment. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical care should be sought. Keep this medication out of the reach of children and do not transfer it to another container.

Side effects

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, increased liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, diminished sensation, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, hallucinations, exacerbation of epilepsy, upper respiratory infection, sinusitis, pharyngitis, rhinitis, bronchial spasm, exacerbated bronchial spasm, shortness of breath, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, arrhythmia, ventricular hypertrophy, angina, unstable angina, coronary artery disorder, myocardial infarction, heart failure, palpitations, tachycardia, cerebral hemorrhage, aortic valve insufficiency, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous inflammation, vasculitis, deep vein thrombosis, unilateral, wound infection, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic disease of the breast, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, liver function abnormalities, increased ALT, increased AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased blood sodium, increased blood potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, appetite loss, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, osteoarthropathy, musculoskeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reactions, hallucinations, cerebral hemorrhage, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized vesicular fixed drug rash, fixed drug rash, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, female infertility

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in an airtight container, preferably at room temperature between 15 degrees and 30 degrees Celsius. Storing it this way helps to maintain the medicine's efficacy for a longer period.

Appearance and packaging

Appearance

An opaque hard capsule that is white with yellowish stripes, containing a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.