Tramacet Sustained-Release Tablet

Adult dose

Adjust the dose according to the patient's level of pain and response to treatment. Administer 1 tablet for the initial dose, and the dosing interval should be at least 12 hours, without exceeding 4 tablets a day. Avoid unnecessary long-term use, and if long-term use is required, conduct regular monitoring of the need for continued use. During administration, side effects such as nausea, vomiting, itching, constipation, dizziness, and drowsiness may occur; thus, the patient's response should be closely monitored and adjusted accordingly.

This medication can cause liver damage; therefore, individuals who regularly consume more than three alcoholic drinks a day should consult a doctor or pharmacist before use. If a rash or allergic reaction occurs during treatment, stop taking the medication immediately and inform healthcare providers. This medication may cause seizures, so patients with a history of seizures or those at high risk of seizures should use it with caution, as the risk of seizures may increase when combined with certain antidepressants or other drugs. Patients with severe respiratory conditions or those experiencing acute asthma attacks may experience life-threatening respiratory depression when taking this medication; thus, it should be administered in a hospital with appropriate equipment. Combining this medication with alcohol or central nervous system depressants, such as benzodiazepines, can lead to severe sedation or respiratory depression and coma, requiring caution. Patients with head injuries or increased intracranial pressure should use this medication cautiously, as respiratory depression may further elevate intracranial pressure. This medication can cause physical and psychological dependence, so careful monitoring is necessary for dependence when used long-term. Patients with impaired liver function or liver disease must consult a physician before taking this medication, and drug manufacturers should check the acetaminophen content to reduce the risk of hepatotoxicity. Individuals with rapid genetic metabolic rates may produce excessive active metabolites from this drug, increasing the risk of side effects such as respiratory depression, and should be careful. It is not safe to use this medication in children under 12 years old or adolescents under 18 years old who have had tonsillectomy or adenoidectomy. This medication may lead to hyponatremia (low blood sodium levels); thus, especially elderly patients or those at risk of hyponatremia should monitor symptoms. Patients with a history of allergy to this medication or those with severe respiratory depression, head injuries, or taking certain medications should not take this medication. Pregnant or breastfeeding women should consult healthcare providers before taking this medication, as it may pose risks to the fetus or newborn. This medication may cause drowsiness or dizziness when driving or operating machinery, so caution is advised. In case of overdose, serious side effects such as respiratory depression and liver damage may occur; therefore, contact a medical institution immediately for appropriate treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, severe allergic reactions, severe skin reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, eyes or skin turning yellow (jaundice), extreme fatigue, liver abnormalities (jaundice), sudden

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• exacerbation of hypertension
• hypotension
• arrhythmia

This medication may be sensitive to air or humidity; therefore, it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to preserve its effectiveness for a longer period.

Appearance

Light yellow rectangular sustained-release film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle