Medication info

Ritostin Tablet 10 mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTabletExpired
Ingredient · strength
Atorvastatin Calcium Trihydrate›10.36mg / 1 tablet
Manufacturer / importer
태극제약(주)
Appearance
White oval film-coated tablet
Packaging
For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle
Approval status
Expired

MFDS item code 201505120 · Approved 2015.07.28

This product's status changed to Expired on 2025.07.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Reduces the risk of myocardial infarction and stroke and improves hyperlipidemia
Who uses it
Adults · Children
Adult dosage
For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily, and for patients needing greater LDL-cholesterol reduction, it can be started at 20 mg or 40 mg once daily. The typical dosing range is 10 - 80 mg once daily. The initial and maintenance doses should be individually adjusted based on therapeutic goals and patient response, with lipid levels analyzed within 2-4 weeks after starting treatment to adjust the dose.
Children's dosage
For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended initial dose is 10 mg once daily, and the maximum recommended dose is 20 mg once daily. The dosage can be adjusted based on therapeutic goals at intervals of more than 4 weeks.

Ingredients

Manufacturer
태극제약(주)

Efficacy & effects

Reduces the risk of myocardial infarction and stroke and improves hyperlipidemia

  • Myocardial infarction
  • stroke
  • vascular revascularization
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication helps reduce the risk of cardiovascular diseases. It lowers the risk of hospitalization due to myocardial infarction, stroke, angina, and congestive heart failure in adult and pediatric patients with multiple risk factors like hypertension, smoking, and diabetes. Additionally, it improves cholesterol and triglyceride levels in patients with primary and mixed dyslipidemia, and increases HDL cholesterol, thus improving blood lipid levels. This drug is used as an effective adjunct treatment for patients with hypercholesterolemia that is difficult to control through diet. It also helps lower total cholesterol and LDL cholesterol levels in pediatric patients with heterozygous familial hypercholesterolemia. Overall, it is used to maintain cardiovascular health and reduce the risk of cardiovascular diseases.

Dosage and Administration

Adult dosage

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily, and for patients needing greater LDL-cholesterol reduction, it can be started at 20 mg or 40 mg once daily. The typical dosing range is 10 - 80 mg once daily. The initial and maintenance doses should be individually adjusted based on therapeutic goals and patient response, with lipid levels analyzed within 2-4 weeks after starting treatment to adjust the dose.

Children's dosage

For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended initial dose is 10 mg once daily, and the maximum recommended dose is 20 mg once daily. The dosage can be adjusted based on therapeutic goals at intervals of more than 4 weeks.

Precautions

This drug can cause muscle problems, so if symptoms of muscle pain or weakness occur, stop using it immediately and consult a doctor. This medication should not be used by patients with poor liver function, specific muscle diseases, pregnant or breastfeeding women, and children under 10 years of age. Patients with a history of liver disease or alcohol addiction need to use this drug with caution, requiring regular liver function tests and health status monitoring. This medication can raise blood sugar levels, so patients at risk of diabetes should manage their blood sugar closely. When taken with specific medications, blood concentration may increase or decrease, so it is essential to inform healthcare providers about concurrent medications as dosage adjustments may be necessary. This drug is contraindicated in pregnant women, and fertile women should take adequate contraception while on this medication. Breastfeeding women should avoid taking this drug, and children or the elderly should be closely monitored due to the higher risk of myopathy. In case of overdose, since there is no specific antidote, treatment should be based on symptoms, and liver function and muscle status should be checked regularly. This medication should be stored out of reach of children and kept in its original container to prevent quality degradation.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, mucocutaneous syndrome, skin peeling, pain in mucous membranes of the mouth/eyes, severe muscle weakness, ophthalmoplegia, rhabdomyolysis, acute renal failure, severe edema, liver failure, jaundice, hepatitis, liver dysfunction, elevated AST levels, severe allergic reactions, severe skin reactions, serious neurological symptoms (e.g.,

Mild side effects

  • Fatigue
  • malaise
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • indigestion
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • taste disturbance
  • amnesia
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it should be kept at a temperature between 1 degree and 30 degrees Celsius at room temperature to maintain its effectiveness.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.