Sitapholmin XR Sustained Release Tablet 50/1000 mg

Adult dose

The 100/1000 mg sustained release tablet is taken once daily, one tablet at a time. Patients taking the 50/500 mg sustained release tablet or the 50/1000 mg sustained release tablet should take two tablets at a time once daily. 1. For patients currently not on metformin treatment: The initial dosage is a total daily dose of 100 mg sitagliptin and 1000 mg metformin. Gradually increase the metformin dose.

This medication contains sitagliptin and metformin, and is used in the treatment of diabetes. While taking this medication, serious allergic reactions may occur rarely. If you experience symptoms such as skin rashes, difficulty breathing, or swelling of the face or neck, discontinue use immediately and consult a doctor. Pancreatitis can cause inflammation of the pancreas; if symptoms such as severe abdominal pain, nausea, vomiting, or fever occur, visit a hospital immediately. This medication should not be administered to patients with impaired kidney function, dehydration, severe infections, or heart failure, and should be discontinued for a period before and after surgery. It is safe for pregnant or possibly pregnant women and nursing mothers not to take this medication. This medication may cause hypoglycemia, so it is advisable to eat regularly and avoid vigorous exercise or alcohol consumption. Elderly patients with impaired kidney function should be particularly cautious and should have regular kidney function tests. During treatment, Vitamin B12 levels may drop, so regular blood tests are necessary, and vitamin supplementation may be needed if symptoms arise. There may be interactions when taken with other medications, so if you are taking other medicines, be sure to inform your doctor or pharmacist. If unusual symptoms such as sudden weight gain, breathlessness, severe joint pain, or skin blisters appear while taking this medication, consult medical personnel immediately. In case of overdose, emergency treatment is required as this medication can be partially removed by hemodialysis. To enhance the therapeutic effect of this medication, it should be combined with dietary therapy and regular exercise, and regular monitoring of blood sugar levels and kidney function should be performed.

Serious side effects

Hives, angioedema, anaphylaxis, Stevens-Johnson syndrome, acute pancreatitis, acute renal failure, lactic acidosis, severe hypoglycemia, acute liver dysfunction (possible elevation of liver enzymes), bullous pemphigoid, severe joint pain, thrombocytopenia

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• myalgia
• limb pain

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its efficacy and safety for a longer period.

Appearance

Light green, bilaterally convex, oval-shaped sustained release film-coated tablet

Package unit

30 tablets/bottle