Lansoprazole Tablets 10 mg (Lansoprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: 10 mg of oral administration once daily; depending on symptoms, 20 mg can be administered orally once daily. Gastric ulcers are administered for 8 weeks, and duodenal ulcers for 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg once daily for 4 to 8 weeks. If not treated after 8 weeks, 10 mg or 20 mg can be given orally twice daily for 8 weeks.

This medication should not be used in patients with hypersensitivity to certain ingredients or benzimidazole derivatives. Additionally, patients with hypersensitivity to penicillin antibiotics or macrolide antibiotics during Helicobacter pylori eradication therapy should avoid its use. It should not be administered to patients taking specific heart-related medications or those on atazanavir or rilpivirine. It is also safer not to use this medication in pregnant or breastfeeding women. Careful administration is needed for patients with poor liver function, elderly patients, and those with a history of drug hypersensitivity. When using this medication, allergic symptoms such as skin rash, hives, or itching may occur; if such symptoms develop, administration should be stopped immediately. Regular blood tests are required as changes in red or white blood cell counts may occur. Liver function tests should also be performed regularly, and if symptoms of hepatitis or jaundice appear, administration should be discontinued. Caution is needed as cardiac symptoms, gastrointestinal issues, and neurological symptoms may occur. Various side effects such as respiratory symptoms, muscle pain, skin rash, and visual disturbances have been reported; therefore, consultation with a healthcare provider is recommended if abnormal symptoms arise. Long-term use may increase the risk of osteoporosis and fractures, and hypomagnesemia may occur, so it is advisable to periodically check serum magnesium levels. This medication can increase the risk of bacterial infection in the stomach by suppressing gastric acid secretion, so if diarrhea or other symptoms persist, consultation with a doctor is necessary. Caution is needed as there is a risk of accidents while driving or operating machinery due to drowsiness. There may be interactions with other medications, so it is important to inform healthcare providers of any other medications being taken, especially when used in combination with warfarin or methotrexate. This medication should be swallowed whole and not chewed or crushed. It should be kept out of reach of children, and it is best not to transfer it to another container. It is safer not to take this medication during pregnancy or breastfeeding, and elderly patients should use it cautiously due to the potential for side effects from decreased liver function. The safety for use in children has not been established; therefore, use in pediatric patients is not advisable. In the case of overdose, as there is no specific antidote, appropriate treatment should be provided based on symptoms, as this medication has a high protein binding rate and is not removed by dialysis. Regular checks and following healthcare provider instructions are essential when using this medication for a prolonged period.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, fever, severe allergic reactions, fulminant hepatitis, liver dysfunction, jaundice, severe neurological symptoms (headache, seizures, confusion, visual disturbances, paralysis, delirium), pulmonary embolism, ventricular tachycardia, thrombophlebitis, toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, hepatic encephalopathy, apnea, respiratory depression, acute interstitial nephritis,

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. The storage temperature should be kept at room temperature between 1 to 30 degrees Celsius. Doing so will help maintain the drug's efficacy and safety for a long time.

Appearance

Pale yellow round enteric-coated tablets

Package unit

28 tablets/box [(28 tablets/PTP*1)]