Selmetek Tablet 40 mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose for adults is 10 mg once daily, regardless of meals. If blood pressure is not adequately controlled, it may be increased to 20 mg once daily. If additional blood pressure reduction is needed, the dose may be increased to a maximum of 40 mg once daily. The antihypertensive effect appears within 2 weeks of starting treatment, with maximum effectiveness noted around 8 weeks. Patients with potential intravascular volume depletion should be closely monitored.

This medication may cause serious harm or death to the fetus and newborn if taken during the second or third trimester of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Individuals allergic to this medication or its ingredients, pregnant or breast-feeding women, patients undergoing dialysis, those with severe liver impairment, and patients with bile duct obstruction should not take this medication. Those with lactose intolerance or certain genetic metabolic disorders should also refrain from using this medication. Patients with decreased blood volume or low salt levels may experience hypotension, so their condition should be monitored closely, and appropriate actions should be taken if hypotension occurs. Patients with severe heart failure or those sensitive to renal function may experience deterioration in kidney function; regular monitoring is necessary when taking this medication. Patients with renal disorders, kidney transplant recipients, or patients with renal artery hypertension may also show changes in kidney function, so close administration is required. Due to the risk of hyperkalemia, serum potassium levels should be checked frequently; patients with aortic stenosis or cardiomyopathy should also be cautious. Dizziness may occur while taking this medication, so it is advisable to avoid driving or operating dangerous machinery. This medication may cause side effects such as dizziness, headache, abdominal pain, and nausea, and rarely has been reported to cause angioedema, liver function abnormalities, hyperkalemia, or renal failure. If chronic diarrhea or weight loss occurs, discontinue use and consult a physician. Drug interactions may occur when taken concurrently with other antihypertensives, potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, etc., so be sure to inform healthcare providers. Pregnant women should not take this medication due to serious risks to the fetus, and breast-feeding mothers should consider discontinuing use or breast-feeding due to potential adverse effects on the infant. Safety in pediatric patients has not been established, and older adults may have higher drug concentrations in the body, requiring caution. Overdosage may lead to hypotension or heart abnormalities, necessitating prompt emergency treatment.

Serious side effects

Hives, severe swelling (including angioedema, facial swelling, peripheral edema), chest pain, anaphylactic reactions, hyperkalemia, acute renal failure, elevated serum creatinine, hives, severe rash with fever, blistering, skin peeling, oral/ocular mucosal pain, severe allergic reactions, liver function abnormalities (increased liver enzymes or bilirubin, autoimmune hepatitis), respiratory problems (asthma, asthma attacks)

Mild side effects

• Dizziness
• low back pain
• bronchitis
• increased creatine phosphokinase
• diarrhea
• headache
• hematuria
• hyperglycemia
• hypertriglyceridemia
• influenza-like symptoms

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 25 degrees Celsius to safely preserve the medication's effectiveness.

Appearance

White, rectangular, film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle