Losarca Tablet 5/50 mg

Adult dose

The recommended dosage for this medication is 1 tablet once daily, taken with water irrespective of meals. It is advisable to take it at the same time daily (e.g., in the morning). Typically, 5/50 mg of this medication is administered once daily, and if blood pressure is not adequately controlled after 2 weeks of treatment, the dosage may be increased to 10/50 mg once daily.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years, thus administration of this drug is not recommended.

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. Care should be taken as hypotension may occur upon initial administration in patients with reduced blood volume. It should not be used in patients with hypersensitivity to any of its components, pregnant or potentially pregnant women, nursing mothers, patients with severe liver impairment, severe aortic stenosis, and those in shock. It should be administered cautiously in patients with decreased blood volume, rigorous sodium restriction, moderate to severe renal impairment, and hyperkalemia. Various side effects like dizziness, headache, drowsiness, edema, blood pressure reduction, dyspepsia, skin rash, etc., may occur; if symptoms are severe, consult a physician. Especially, dizziness may occur due to the blood pressure-lowering effect, thus avoiding dangerous activities like working at heights or operating vehicles is advisable. It is safer to avoid this drug during lactation as it may be excreted in breast milk. This drug is not recommended for children under 18 years, as the safety and efficacy have not been established. Caution is needed for elderly patients over 75 years as appropriate dosage adjustment may be difficult. When taken with other antihypertensives, caution must be exercised according to a physician's instructions, as the effects may be enhanced. Overdosing may result in severe hypotension or cardiac issues, so adherence to prescribed doses is crucial, and medical attention should be sought immediately if adverse symptoms occur. Store out of reach of children and do not transfer the drug to another container to maintain its quality.

Serious side effects

Hives, angioedema (causing airway obstruction with laryngeal/pharyngeal swelling of the glottis, swelling of the face/lips/pharynx/tongue), severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, skin peeling, pain in mucous membranes of the mouth/eyes, dyspnea, asthma attack, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of the skin or eyes), pronounced lethargy, sudden and severe.

Mild side effects

• Dizziness
• headache
• drowsiness
• weakness
• chest discomfort
• chest pain
• early satiety
• peripheral edema
• pitting edema
• abdominal discomfort

This medication should be stored in a tightly closed container to protect it from air and moisture. It is also important to keep it at room temperature between 1 and 30 degrees Celsius to maintain its effectiveness.

Appearance

White rectangular film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, for export - 30 tablets/box [(10 tablets/PTPX3)]