Hyniz Olmesartan Medoxomil Tablets

Adult dose

The recommended initial dose is 10 mg once daily, regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20 mg once daily. It can be increased up to a maximum of 40 mg daily. The blood pressure-lowering effect is observed within 2 weeks after starting treatment, with maximum effect occurring around 8 weeks. It can be administered in combination with thiazide diuretics such as hydrochlorothiazide.

Child dose

The safety and efficacy in children have not been established.

This medication can cause severe harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Patients with hypersensitivity to this drug or any of its components, pregnant or lactating women, patients on renal dialysis, patients with severe liver dysfunction, patients with biliary obstruction, and those with genetic issues such as lactose intolerance should not take this medication. In patients with reduced blood volume or sodium, hypotension may occur, so conditions should be checked before taking the drug, and hypotension symptoms should be closely monitored during use. Patients with impaired kidney function or kidney transplant recipients should regularly check potassium and creatinine levels through blood tests, and it is not recommended for patients with severe renal impairment. Due to the risk of hyperkalemia, particularly in patients with heart failure or renal impairment, serum potassium levels should be monitored closely. This drug has a blood pressure-lowering effect, so dizziness may occur; it is advisable to avoid dangerous activities such as operating machinery or driving while taking it. During the use of this medication, liver function and blood pressure should be regularly checked, and if symptoms such as chronic diarrhea or abdominal pain occur, medical consultation should be sought immediately. Caution is needed when taken with other antihypertensives, potassium-sparing diuretics, or potassium supplements, as potassium levels may increase. When taken with lithium, blood lithium levels may increase, potentially leading to toxicity, and such co-administration is not recommended. Co-administration with non-steroidal anti-inflammatory drugs may worsen renal function, so it is necessary to maintain adequate hydration and monitor renal function. If a pregnant woman takes this medication, there is a risk of decreased renal function in the fetus, oligohydramnios, and neonatal death, so it should not be taken during pregnancy, and it is essential to consult a physician if pregnancy is planned or confirmed. Lactating women should be aware that this medication may be passed into breast milk and could cause adverse reactions in infants, so it is advisable to either discontinue breastfeeding or stop the medication. The safety and efficacy for children have not been established, so it is not advised for pediatric use. In case of overdose, symptoms such as hypotension, palpitations, and bradycardia may occur, and immediate medical attention should be sought for appropriate treatment. There is no evidence of carcinogenic or genotoxicity after long-term use of this medication, but if abnormal symptoms occur during use, consult a physician immediately.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, acute renal failure, hyperkalemia, urticaria, liver function abnormalities (increased liver enzymes or bilirubin), severe edema, increased blood pressure, asthma attack, severe allergic reactions

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• cough
• nasal bleeding
• upper respiratory tract infection
• asthma
• nausea
• diarrhea

This medication should be stored in a sealed container to protect it from air or moisture and kept at room temperature between 1 to 25 degrees Celsius. Proper storage can maintain the efficacy of the medication and prevent degradation.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle