Micardis Plus Tablets 40/12.5 mg

Adult dose

In patients where blood pressure is not adequately controlled with telmisartan alone, this medication should be taken once daily with water, regardless of meals. It is recommended to adjust each component dose individually before switching to this fixed-dose formulation. When clinically appropriate, switching directly from monotherapy to this combination medication can also be considered. - Telmisartan/Hydrochlorothiazide combination 40/12.5 mg can be administered to patients whose blood pressure is not adequately controlled with 40 mg telmisartan alone. - Telmisartan/Hydrochlorothiazide combination 80/12.5 mg can be administered to patients whose blood pressure is not adequately controlled with 80 mg telmisartan alone. - Telmisartan/Hydrochlorothiazide combination 80/25 mg can be administered to patients whose blood pressure is not adequately controlled with either 80 mg telmisartan in combination with 12.5 mg hydrochlorothiazide alone or with other medications. Before starting this medication, sodium or volume depletion should be corrected. Kidney Impairment Patients No dose adjustment is required for patients with mild to moderate renal impairment. This medication is not to be administered to patients with severe renal impairment (creatinine clearance <30 mL/min). Regular monitoring of renal function is recommended. Liver Impairment Patients Caution is advised when administering this medication to patients with mild to moderate liver impairment. The dose should not exceed 40/12.5 mg daily. This medication is contraindicated in patients with severe liver impairment (refer to precautions 2). Thiazide diuretics should be administered cautiously in patients with liver dysfunction. Elderly Patients No dose adjustment is necessary. Pediatric Patients The safety and efficacy of this medication have not been established in pediatric patients under the age of 18.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under the age of 18.

This medication should not be used in pregnant women as it can cause serious harm or death to the fetus or newborn, especially during the second and third trimesters. It should not be administered to individuals allergic to the active ingredients or excipients, those with hypersensitivity to sulfonamide drugs, pregnant or breastfeeding women, individuals with bile duct obstruction or cholestasis, those with severe liver or kidney impairment, and specifically those with certain kidney diseases or electrolyte imbalances. Elderly patients, those with high potassium levels, individuals with liver disorders, heart valve diseases, ischemic heart disease, gastrointestinal disorders, and renal vascular hypertension should use this medication with caution, as there may be an increased risk of skin cancer; they should avoid sun exposure and regularly monitor their skin condition. When taking this medication, various side effects such as dizziness, hypotension, electrolyte imbalance, and liver dysfunction may occur, so any unusual symptoms should be discussed with a healthcare professional immediately. This medication may affect kidney function, so kidney function and serum electrolyte levels should be monitored regularly, and interactions may occur when taken with other blood pressure medications, diuretics, lithium, and non-steroidal anti-inflammatory drugs, so it is essential to inform your doctor or pharmacist. Pregnant women or those planning to become pregnant should not use this medication, and breastfeeding women should also refrain from taking it. In case of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration can occur, so immediate medical attention should be sought for appropriate treatment. This medication is not recommended for children under the age of 18, as its safety and efficacy have not been established. Caution is advised while driving or operating machinery, as dizziness or drowsiness may occur during treatment. This medication should be stored in a cool, dry place away from direct sunlight and kept out of reach of children, and it should be removed from the packaging immediately before use.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning bolt headache, seizures, confusion of consciousness, visual disturbances, paralysis,

Mild side effects

• Bronchitis
• pharyngitis
• sinusitis
• hypokalemia
• hyperuricemia
• hyponatremia
• anxiety
• depression
• insomnia
• sleep disturbances

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius. This helps to preserve the medication's efficacy over time.

Appearance

Oval tablets consisting of two layers, white and pink, with possible pink speckles on the white layer.

Package unit

30 tablets (10 tablets/PTP packaging, 3 packs)