Unicita Tablets 100 mg (Sitagliptin Phosphate Hydrate)

Adult dose

This medication is administered once daily at 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken regardless of meals. Dosage adjustment in patients with renal impairment: 1. Mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment needed 2. Moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): No dosage adjustment needed 3. Moderate

This medication may cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a physician. This medication may cause serious pancreatic disorders, such as acute pancreatitis, so if abdominal pain, vomiting, or persistent abdominal discomfort occurs, notify healthcare professionals immediately. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and should be avoided if there is an allergy to this medication or its components. Patients with impaired renal function must adjust the dosage of this medication, so regular kidney function tests should be performed, and it should be taken according to a physician's instructions. Hypoglycemic symptoms may occur during the use of this medication; particularly when taking insulin or sulfonylureas, blood glucose levels should be monitored closely. Severe joint pain or blistering skin conditions may occur; if symptoms appear, consult a physician immediately for appropriate treatment. Use during pregnancy or breastfeeding is not recommended, and safety and effectiveness have not been established for children or adolescents under 18 years of age. Elderly patients may have impaired renal function, so it is important to regularly check kidney function before and after taking this medication. In case of overdose, appropriate treatment should be received immediately at a hospital, and this medication can be partially removed by hemodialysis. There may be drug interactions when taken with other hypoglycemic agents, so if you are taking other medications, it is essential to inform your physician or pharmacist. Generally, this medication has been confirmed for cardiovascular safety, but it is necessary to consult a specialist immediately if adverse reactions occur.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
• Severe rash accompanied by high fever, blisters, skin peeling, pain in mouth/eyes → severe skin adverse reaction
• Acute pancreatitis (including hemorrhagic or necrotizing pancreatitis)
• Shortness of breath or difficulty breathing, asthma attacks, cough + fever accompanied respiratory abnormalities
• Skin or eyes turning yellow (jaundice), systemic malaise

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

This medication should be stored in a tightly closed container to prevent air ingress, at a temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication.

Appearance

Beige round, biconvex film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP×2)]