Ilseong Sitagliptin Tablet 100 mg (Sitagliptin Phosphate)

Adult dose

This medication is administered at a dose of 100 mg once daily for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken without regard to meals. For patients with renal impairment, dosage adjustment is necessary based on renal function. - Mild renal impairment (eGFR 60 or above and below 90): No dose adjustment required - Moderate renal impairment (eGFR 45 or above and below 60): No dose adjustment required - Moderate renal impairment

This medication may cause severe allergic reactions, so if symptoms such as rash or difficulty breathing occur, discontinue use immediately and consult a doctor. While taking this medication, inflammation of the pancreas, known as pancreatitis, may occur, so it is essential to inform healthcare personnel if symptoms such as abdominal pain, nausea, or vomiting arise. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, and individuals with severe allergies to the medication or its components should avoid its use. In cases of poor kidney function, dosage adjustment of this medication is required, so patients with kidney diseases must consult a doctor. This medication can be used alone or in combination with other diabetes treatments, but special care should be taken to recognize hypoglycemic symptoms, especially when used with drugs that can cause hypoglycemia, such as insulin or sulfonylureas. In clinical trials, side effects such as headaches, upper respiratory infections, rhinitis, and diarrhea have been reported; thus, if these symptoms persist or worsen, inform a doctor. This medication is not recommended for pregnant women, and nursing mothers should also avoid its use. Elderly patients may have reduced kidney function, so regular kidney function assessments are necessary before and after the use of this medication. In cases of overdose, appropriate treatments such as gastrointestinal decontamination and ECG monitoring should be provided, and it may be partially removed by hemodialysis. If symptoms such as joint pain or skin blisters occur during the use of this medication, consult a doctor immediately, as these symptoms may improve with discontinuation of the drug. Drug interactions are relatively few, but take care when used in conjunction with cyclosporine or digoxin, so inform your doctor of any medications you are taking.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin disorders (including Stevens-Johnson syndrome), severe skin adverse reactions, acute pancreatitis, severe allergic reactions, acute renal failure, severe and disabling joint pain, bullous pemphigoid, jaundice (liver dysfunction), severe hypoglycemia, pneumonia, diabetes complications, metabolic acidosis, falls, cardiac arrest, rhabdomyolysis, angioedema

Mild side effects

• Upper respiratory infections
• rhinitis
• headache
• nausea
• diarrhea
• abdominal pain
• constipation
• muscle pain
• limb pain
• back pain

This medication should be stored in a tightly closed container to prevent the ingress of air or moisture. It is advisable to store it at room temperature, between 1 degree and 30 degrees Celsius. This helps maintain the medication's efficacy and prevent degradation.

Appearance

Beige-colored, double convex, round, film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3 pieces)]