Bonmarine Injection (Cholecalciferol)

Adult administration

Used according to a doctor's prescription, adjusting dosage based on the blood level of 25-hydroxyvitamin D. For adults, administer 200,000 IU of cholecalciferol by intramuscular injection. Annual dosage should not exceed 600,000 IU of cholecalciferol.

Child administration

For adolescents, administer 200,000 IU of cholecalciferol by intramuscular injection.

This drug contains vitamin D, and overdose can cause side effects. Therefore, total vitamin D intake should be checked when used in conjunction with other treatments or fortified foods containing vitamin D. If blood calcium levels become too high or the amount of calcium excreted in urine exceeds certain criteria, discontinue use of this medication. Regular checks of blood and urine calcium levels are necessary if calcium intake is high. Care should be taken when cutting the container to avoid glass fragments in injectable solutions, especially when using in children or the elderly. Do not use in case of allergic reactions, hypercalcemia, kidney stones, renal dysfunction, bedridden patients, patients with specific diseases, and women who are pregnant or breastfeeding. Various side effects such as headaches, muscle pains, digestive issues, dehydration, elevated blood pressure, and kidney problems can occur during treatment; if symptoms arise, consult with medical personnel immediately. Regular testing is required for those with low or high blood vitamin D levels and especially elderly patients or those taking certain medications should frequently check kidney function. Caution is needed when taken with other medications like anticonvulsants, diuretics, antacids, and warfarin; always inform medical staff of medications being taken. This drug should not be used during pregnancy, and its safety and efficacy are not sufficiently confirmed for children, so usage should be avoided. In case of overdose, immediately stop this medication, reduce calcium intake, ensure adequate hydration, and take measures to promote diuresis. This medication should not be mixed with others and should be used as soon as possible after opening, discarding any leftover drug. Store in a sealed container that blocks light, and maintain storage temperature between 1 to 25 degrees Celsius.

Serious side effects

• Hypercalcemia
• kidney dysfunction
• arrhythmia
• rash
• urticaria

Mild side effects

Headaches, weakness, fatigue, muscle pains, loss of appetite, weight loss, stunted growth, nausea, vomiting, constipation, diarrhea, polydipsia, polyuria, dehydration, hypertension, calcium stones, tissue calcification in the kidneys and blood vessels, kidney problems, excessive bone calcification, arrhythmia, mental symptoms, body awareness disturbances, joint pain, myasthenia, drowsiness, azotemia, hypersensitivity reactions, thirst, confusion, bloating, abdominal pain, metallic taste, dry mouth, rash, itching, hypercalciuria,

This medication should be stored in a sealed container that blocks light, maintaining a storage temperature between 1 to 25 degrees Celsius. This will help preserve the drug's effectiveness and prevent deterioration.

Appearance

A transparent liquid with a light yellow color in a brown glass ampoule.

Package unit

10 ampoules per box [(1.5mL/ampoule)], 10 ampoules per box [(1mL/ampoule)]