Janusita Tablet 50 mg (Sitagliptin Phosphate)

Adult dose

This medication is administered at a dose of 100 mg once daily, whether used alone or in combination, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Dosage adjustment based on kidney function is necessary. - No dosage adjustment is needed for patients with mild renal impairment. - For patients with moderate renal impairment (glomerular filtration rate of 30–45 mL/min/1.73 m2), administer 50 mg once daily. - For severe renal impairment (glomerular filtration rate of

This medication may cause severe hypersensitivity reactions, so if symptoms such as skin rash, angioedema, or difficulty breathing occur within 3 months after administration, usage should be immediately discontinued and medical attention sought. Acute pancreatitis may occur during the use of this drug; therefore, if symptoms such as abdominal pain, vomiting, or persistent abdominal discomfort appear, medical personnel should be informed immediately. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Patients with hypersensitivity to this drug or its components should not take it. Patients with decreased kidney function may need dosage adjustment; it is important to perform kidney function tests before administration. Hypoglycemia symptoms may occur while taking this drug, so blood sugar should be monitored regularly, especially when taken with insulin or sulfonylureas. Severe joint pain or blistering skin conditions may arise; consult a physician immediately if such symptoms occur. It is safer for pregnant or breastfeeding women not to take this drug. Elderly patients may have reduced kidney function, requiring dosage adjustments and kidney function testing. In case of overdose, immediate hospital visit for appropriate treatment is necessary; this drug can be partially removed by hemodialysis. Due to the potential for drug interactions, inform your doctor or pharmacist if you are currently taking any medications.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, anaphylaxis, angioedema, severe allergic reactions, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, Stevens-Johnson syndrome, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, liver abnormalities (jaundice), yellowing of skin or eyes, extreme fatigue

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• constipation
• vomiting
• headache
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in an airtight closed container, kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the drug.

Appearance

Bright beige, bilaterally convex, round film-coated tablet

Package unit

30 tablets/box [10 tablets/PTPX3 units]