Sitagliptin tablets 100 mg (Sitagliptin Phosphate Hydrate)

Adult dose

This medication is administered as 100 mg once daily in monotherapy or combination therapy, and the maximum daily dosage is 100 mg. For patients with kidney impairment, dose adjustments are necessary based on kidney function. Mild and some moderate kidney impairment patients do not require dose adjustments, while in patients with moderate kidney impairment (glomerular filtration rate 30-45 mL/min/1.73 m2), the dosage is 50 mg once daily. In severe renal impairment (glomerular filtration rate 15-

This medication may cause severe hypersensitivity reactions after administration, so if allergy symptoms are suspected, it should be discontinued immediately, and medical attention should be sought. During the use of this medication, attention should be paid to symptoms of acute pancreatitis, and if pancreatitis is suspected, discontinue the medication and consult healthcare personnel immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Patients who have had allergic reactions to this medication or its components should not take it. Patients with impaired kidney function need to adjust the dosage of this medication, and periodic kidney function tests are important. There is a risk of hypoglycemia when taking this medication, especially when taken with insulin or Sulfonylurea, so blood sugar should be carefully monitored, and dosage adjustments may be necessary. Severe joint pain or bullous skin disorders may occur, so if these symptoms appear, consult a doctor immediately. Pregnant or nursing women are advised to avoid taking this medication, and safety and efficacy have not been confirmed in children and adolescents under 18 years of age. Elderly patients may be at risk of impaired kidney function, so dosage adjustments and kidney function monitoring are necessary. In case of overdose, general emergency treatment should be carried out, and if necessary, some medications may be removed via hemodialysis. This medication has relatively few interactions when combined with other diabetes medications or certain drugs, but caution is needed when used with specific medications. If unusual symptoms or discomfort occur while taking the medication, consult healthcare personnel immediately.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness (anaphylaxis and severe allergic reactions), severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa (severe skin adverse reactions), shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanying respiratory abnormalities, yellowing of skin or eyes (jaundice), generalized severe malaise (liver abnormalities), thyroid dysfunction

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent air from entering and kept at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication.

Appearance

Beige colored, round, double-sided convex film-coated tablets

Package unit

In-house packaging unit