Starzin 100 mg (Sitagliptin Phosphate)

Adult dose

This medication is administered at a dose of 100 mg once daily for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken without regard to meals. For patients with renal impairment, dosage adjustment is necessary. - Mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment necessary - Moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): Dosage adjustment

This medication may very rarely cause severe allergic reactions after administration; hence, if symptoms like skin rash or difficulty breathing occur, usage should be stopped immediately and a doctor should be consulted. There are reports of a serious side effect called acute pancreatitis, which is inflammation of the pancreas, so if symptoms such as abdominal pain or vomiting manifest, immediate medical attention is required. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, nor should anyone who is allergic to this drug or its ingredients. Patients with impaired kidney function may need dosage adjustments; therefore, those with kidney disease should inform their doctor. Hypoglycemic symptoms may occur when using this medication, particularly when taken together with insulin or sulfonylureas, so blood sugar levels should be checked frequently and hypoglycemic symptoms should be monitored closely. Rarely, side effects such as arthralgia or the formation of blisters on the skin have been reported; if such symptoms occur, immediate communication with healthcare personnel is necessary. Pregnant or breastfeeding women are advised against using this medication, and safety has not been established for children under 18 years of age. Elderly patients may have decreased kidney function, so it is important to have kidney function tests before taking this medication and to regularly check kidney status during use. In the case of overdose, while standard treatment is generally applied, dialysis may be performed if necessary to remove the medication, so caution should be exercised to avoid exceeding the recommended dose. Finally, this medication may interact with other diabetes treatments or certain medications; thus, all currently taken medications should be disclosed to a doctor and used according to their guidance.

Serious side effects

• Urticaria, severe swelling (edema), anaphylaxis, angioedema, rash, exfoliative skin diseases including Stevens-Johnson syndrome, severe allergic reactions
• Acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis), elevated liver enzyme levels, acute renal failure, severe arthralgia with disability, bullous pemphigoid, rhabdomyolysis
• Difficulty breathing, asthma attacks, and other respiratory issues
• Symptoms related to liver abnormalities (jaundice)

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent exposure to air, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over time.

Appearance

Beige, bilaterally convex, round film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP X 3]