Janugliptin 50 Milligrams (Sitagliptin Phosphate)

Adult dose

This medication is administered once daily at a dosage of 100 mg as either monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, a dosage of 50 mg once daily is given for moderate renal impairment (glomerular filtration rate 30-45 mL/min/1.73 m2). For patients with severe renal impairment (glomerular filtration rate 15-30 mL/min/1.73 m2) or end-stage renal disease (E

This medication may cause allergic reactions; therefore, if symptoms such as skin rash, itching, or difficulty breathing occur after taking the medication, discontinue use immediately and consult a doctor. Severe pancreatitis may occur within the first 3 months of starting therapy; immediately visit a hospital if experiencing abdominal pain, vomiting, or severe discomfort in the abdomen. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, nor should those allergic to this drug or its ingredients. Patients with decreased kidney function must adjust the dosage of this medication, requiring periodic kidney function tests. When used in conjunction with other antihyperglycemic agents, particularly insulin or Sulfonylurea, there is an increased risk of hypoglycemia, necessitating frequent monitoring of blood sugar levels and dose adjustments as needed. Serious adverse effects such as severe joint pain or bullous skin disorders can occur, so report any such symptoms to a doctor immediately. Pregnant or breastfeeding women are advised to avoid taking this medication, and safety for children and adolescents under 18 years has not been established. In case of overdose, seek immediate medical care as appropriate treatment is needed; this medication can be partially removed by dialysis. This medication generally confirms cardiovascular safety; however, greater caution is needed in elderly or those with impaired kidney function.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, rash, Stevens-Johnson syndrome, exfoliative skin disorders, severe allergic reactions, acute pancreatitis, pancreatitis, difficulty breathing, acute renal failure, elevated liver enzymes, joint pain (with severe or disabling complications), bullous pemphigoid, rhabdomyolysis, pneumonia, diabetic complications, metabolic acidosis, falls, cardiac arrest

Mild side effects

• Pharyngitis
• upper respiratory tract infection
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication must be stored in a tightly sealed container to prevent air from entering, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage maintains the efficacy of the medication and ensures safe use.

Appearance

Bright beige, biconvex circular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]