Sitavia 100 mg Tablets (Sitagliptin Phosphate)

Adult dose

This medication is administered once daily at a dose of 100 mg when used alone or in combination, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dose adjustments are necessary based on renal function. - Mild renal impairment: No dose adjustment required - Moderate renal impairment (eGFR 45-60): No dose adjustment required - Moderate renal impairment (eGFR 30-45): 1 day

This medication may cause severe allergic reactions, so if symptoms such as rash, difficulty breathing, or swelling of the face or neck appear after administration, use should be stopped immediately and a physician consulted. During treatment, if symptoms of acute pancreatitis such as severe abdominal pain, vomiting, or fever occur, stop taking the medication and inform medical personnel immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, nor should individuals allergic to this medication or its components. Patients with impaired kidney function need to be cautious with this medication’s dosage, and routine kidney function tests before and during treatment are important. Hypoglycemia may occur when this medication is used alone or in combination with other diabetes medications, particularly when used with insulin or sulfonylureas. Rare side effects such as severe joint pain or blistering conditions similar to pemphigus have been reported, so if such symptoms occur, notify a doctor immediately. The use of this medication is not recommended for pregnant or breastfeeding women, and safety in pediatric patients under 18 years old has not been established. In case of overdose, general emergency treatments such as gastrointestinal decontamination may be needed, and this medication can be partially removed by hemodialysis. This medication does not significantly impact cardiovascular safety, but regular health check-ups and consultations with healthcare professionals are necessary during administration.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• severe joint pain with disability
• pemphigus-like blistering
• acute kidney failure
• elevated liver enzymes

Mild side effects

• Upper respiratory tract infections
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a sealed container to prevent air ingress and is best kept at room temperature between 1°C and 30°C. This will help maintain the drug's efficacy and prevent degradation.

Appearance

Beige, convex, round film-coated tablet on both sides

Package unit

30 tablets (10 tablets/PTPX3)