Medication info
Cozartan-X Tablet 5/50 mg (Amlodipine, Losartan Potassium)

Cozartan-X Tablet 5/50 mg (Amlodipine, Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.944mg / 1 tabletLosartan Potassium›50mg / 1 tablet
Manufacturer / importer
영풍제약(주)
Appearance
White oblong film-coated tablet
Packaging
30 tablets/bottle. 300 tablets/bottle
Approval status
Active

MFDS item code 201502670 · Approved 2015.04.30 · Insurance code 661904520

Summary

Main use
Improvement in blood pressure control for essential hypertension and stage 2 hypertension
Who takes it
Adults · Children
Adult dose
The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Typically, this medication 5/50 mg is administered once daily, and if blood pressure is not sufficiently controlled after 2 weeks of administration, the dose may be increased to 10/50 mg once daily.
Child dose
Safety and efficacy have not been established for pediatric patients under 18 years of age, so the use of this medication is not recommended.

Ingredients

Manufacturer
영풍제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension and stage 2 hypertension

  • Essential hypertension
  • stage 2 hypertension
View approved original text

This medication is used in patients with essential hypertension who have difficulty controlling blood pressure with either amlodipine or losartan monotherapy. It is particularly prescribed as initial therapy when combination therapy is required to achieve treatment target blood pressure in patients with stage 2 hypertension. These drugs help effectively lower blood pressure and reduce the risk of cardiovascular diseases.

How to take

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Typically, this medication 5/50 mg is administered once daily, and if blood pressure is not sufficiently controlled after 2 weeks of administration, the dose may be increased to 10/50 mg once daily.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years of age, so the use of this medication is not recommended.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. There may also be risks to the fetus in early pregnancy, so women who may become pregnant should avoid taking this medication. Patients with low blood volume or those taking diuretics should manage their condition well prior to taking this medication, as there may be a risk of a sudden drop in blood pressure. Patients with allergies to any of its components or severe liver or heart disease should avoid taking this medication. Elderly patients or those with renal impairment may require dosage adjustments and should take it cautiously after consulting a healthcare professional. Dizziness or drowsiness may occur during usage, so it is advisable to avoid driving or operating hazardous machinery. For patients taking other antihypertensive medications or potassium-sparing diuretics, the blood pressure-lowering effect may become excessive, so it is important to inform the healthcare professional about current medications. This medication should not be administered during breastfeeding, and its safety has not been established in children, so its use is not recommended. Taking an overdose may lead to severe hypotension and heart problems, so it is essential to adhere strictly to the dosage, and if unusual symptoms occur, a healthcare facility should be visited immediately. This medication should be stored out of reach of children, and it is advisable not to transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Rash, angioedema (swelling of the lips and eyelids and facial rash), angioedema (swelling of the larynx/larynx that can cause airway obstruction, and swelling of the face/lips/pharynx/tongue), anaphylactic reaction, severe allergic reaction, vasculitis (Henoch-Schönlein purpura), acute hepatitis, fulminant hepatitis, hepatitis, liver dysfunction, jaundice, thrombocytopenia, stroke, cerebrovascular accident (CVA), myocardial infarction, obstructive shock,

Mild side effects

Dizziness, headache, drowsiness, weakness, discomfort in the chest, chest pain, early satiety, peripheral edema, pitting edema, discomfort in the abdomen, dyspepsia, nausea, gastroesophageal reflux, constipation, itching, rash, palpitations, flushing, orthostatic hypotension, facial flushing, dyspnea, cough, conjunctival injection, urinary frequency, drowsiness, stroke, blood pressure reduction, sinoatrial block or atrioventricular block, abdominal discomfort, epigastric pain, diarrhea, loose stools, constipation, skin erythema, petechiae

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a well-closed container to protect it from air and moisture. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This will help preserve the medication's effectiveness.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle. 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.