Medication info
Hiroten Tablets 10/50 mg (Amlodipine, Losartan Potassium)

Hiroten Tablets 10/50 mg (Amlodipine, Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›13.888mg / 1 tabletLosartan Potassium›50mg / 1 tablet
Manufacturer / importer
(주)메디카코리아
Appearance
Pink oblong film-coated tablet
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 201502666 · Approved 2015.04.30 · Insurance code 646004000

Summary

Main use
Improvement of blood pressure control in essential hypertension and stage 2 hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage for adults is one tablet taken once daily, with or without food, and it is recommended to take it with water. It is advisable to take it at the same time each day, preferably in the morning. Typically, this medication 5/50 mg is administered once daily, and if blood pressure is not adequately controlled after two weeks of treatment, the dosage may be increased to 10/50 mg once daily.
Child dose
The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, so its use is not recommended.

Ingredients

Manufacturer
(주)메디카코리아

Efficacy & effects

Improvement of blood pressure control in essential hypertension and stage 2 hypertension

  • Essential hypertension
  • stage 2 hypertension
View approved original text

This medication is used in patients with essential hypertension whose blood pressure is not adequately controlled with either amlodipine or losartan monotherapy. Additionally, it is used as initial treatment in patients with stage 2 hypertension who require combination therapy to reach their target blood pressure. It helps reduce the risk of cardiovascular diseases and improve health through hypertension management.

How to take

Adult dose

The recommended dosage for adults is one tablet taken once daily, with or without food, and it is recommended to take it with water. It is advisable to take it at the same time each day, preferably in the morning. Typically, this medication 5/50 mg is administered once daily, and if blood pressure is not adequately controlled after two weeks of treatment, the dosage may be increased to 10/50 mg once daily.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, so its use is not recommended.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so women who are pregnant or may become pregnant should avoid use. If pregnancy is confirmed, this medication should be discontinued immediately, and special care is needed for the health of the fetus and newborn. Patients with reduced intravascular blood volume, such as those taking diuretics, should stabilize their condition before taking this medication and should be cautious as hypotension may occur. Patients allergic to any component of this medication, patients with severely impaired liver function, those with severe aortic stenosis, or those in a state of shock should not use this medication. This drug is used for hypertension treatment, and because of its blood-pressure-lowering effect, dizziness or drowsiness may occur, so driving or operating hazardous machinery is not recommended. Patients with impaired liver or kidney function should take this medication with caution, and regular blood tests are recommended as potassium levels may increase. There may be interactions when used with other antihypertensive agents, potassium-sparing diuretics, or potassium supplements, so consultation with healthcare professionals is essential. Nursing mothers should avoid taking this medication as its components may be passed into breast milk. The safety and efficacy of this medication have not been established in children under 18 years of age, and it is not recommended. Overdose may result in severe hypotension or cardiac arrhythmias, so strict adherence to the prescribed dosage is necessary, and if abnormal symptoms occur, immediate medical attention should be sought. This medication should be kept out of reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination abnormalities

Mild side effects

  • Dizziness
  • headache
  • drowsiness
  • weakness
  • chest discomfort
  • chest pain
  • early fullness
  • peripheral edema
  • pitting edema
  • abdominal discomfort
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  • dyspepsia
  • nausea
  • gastroesophageal reflux
  • constipation
  • itching
  • rash
  • palpitations
  • flushing
  • orthostatic hypotension
  • conjunctival injection
  • frequent urination
  • malaise
  • fatigue
  • insomnia
  • heaviness
  • heat sensation
  • impaired glucose tolerance
  • frailty
  • muscle cramps
  • low back pain
  • leg pain
  • congestion
  • upper respiratory tract infection
  • sinusitis
  • diarrhea
  • cough
  • sinus disorders
  • pharyngitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the medication's effectiveness and safety for a long time.

Appearance and packaging

Appearance

Pink oblong film-coated tablet

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.