Amlozal Tablet 5/50 mg (Amlodipine Besylate, Losartan Potassium)

Adult dose

The recommended dose is one tablet once a day, taken with water regardless of meals. It is advised to take it at the same time every day (e.g., morning). Generally, this medication is administered at 5/50 mg once daily, and if blood pressure remains insufficiently controlled after two weeks, the dose may be increased to 10/50 mg once daily.

Child dose

Safety and efficacy for patients under 18 years of age have not been established; therefore, administration of this medication is not recommended.

This medication can cause serious harm to the fetus during pregnancy, especially in the second and third trimesters, so treatment should be discontinued immediately upon confirmation of pregnancy. Due to its potent blood pressure-lowering effects, hypotensive symptoms may occur when first administered to patients with low blood volume or those taking diuretics, so caution is advised. Patients allergic to any components of this medicine, those with severe liver dysfunction, severe aortic stenosis, or those in a state of shock should not take this medication. Patients with elevated potassium levels in the blood, severely impaired renal function, those on strict salt restrictions, and those with low blood volume should use this medicine cautiously. While taking this medication, side effects such as dizziness, headache, drowsiness, itching, swelling, indigestion, orthostatic hypotension may occur, so caution is advised. This medication may pose a risk of accidents due to dizziness when driving or operating dangerous machinery, so caution is necessary. Patients with impaired liver or kidney function may have increased concentrations of this medication in their body, necessitating special caution. When taken with other antihypertensive medications, it may enhance blood pressure-lowering effects, so it is necessary to follow a doctor's guideline. Grapefruit juice may increase blood pressure-lowering efficacy, so it is advisable not to take them together. Pregnant or breastfeeding women should not take this medication, and particularly in the case of a confirmed pregnancy, should stop taking it immediately. This medication is not recommended for patients under 18 years of age as safety and efficacy are not established. Overdosage may lead to severe hypotension and cardiac problems, so dosage should be strictly followed, and emergency medical attention is required in case of overdose. Store out of reach of children, and do not transfer to another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, pain in the oral/eye mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough + fever, yellowing of skin or eyes (jaundice), severe lethargy, liver abnormalities (jaundice), sudden and severe reactions.

Mild side effects

• Dizziness
• headache
• drowsiness
• weakness
• chest discomfort
• chest pain
• early satiety
• peripheral edema
• pit edema
• abdominal discomfort

This medicine should be stored in a tightly sealed container to protect it from air and moisture, at room temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medicine for a longer period.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle