Lephisajung (gefitinib)

Adult dose

Adults: Take 1 tablet orally once daily. This medicine may be taken with or without food at approximately the same time each day. Swallow this medicine whole with water, or, if you are unable to swallow the tablet whole, it may be dispersed in water (non-carbonated water) before administration. Do not use any other beverage. Do not crush the tablet. Place it in half a glass of drinking water and stir occasionally until the tablet disperses (up to 20 minutes), then drink immediately once dispersion is complete. Rinse the glass with half a glass of water and drink. The dispersion may also be administered through a nasogastric tube or gastrostomy tube.

This medication is used in the treatment of lung cancer, and before administration, patients should be adequately informed about the effects and side effects of this medication, particularly about early abnormal symptoms such as dyspnea. Interstitial lung disease, a serious lung condition, may occur in some patients taking this medication and can be fatal, so respiratory symptoms should be carefully monitored. If abnormal symptoms occur, administration should be immediately discontinued, and professional examination should be sought, with appropriate treatment required upon confirmation. This medication should not be administered or should be used with caution in patients with impaired liver or kidney functions, those with specific genetic disorders, and nursing mothers. Various side effects such as diarrhea, skin rashes, and vomiting may commonly occur, and if symptoms arise, consultation with medical personnel is necessary. This medication may interact with other drugs, so if other medications are being taken, be sure to inform medical personnel. Women who are pregnant or may become pregnant should consult a doctor due to the risks associated with this medication, and it should not be used during breastfeeding. When taking the medication, it is to be taken after removing from the packaging and only the tablet should be ingested, storing away from children's reach. If a dose is missed and it is within 12 hours, do not take the missed dose but continue with the next scheduled dose, avoiding double dosing. This medication should be administered by an experienced physician in a specialized medical institution, and it is important to continuously monitor the patient's health status during administration.

Shortness of breath, interstitial lung disease, cough, fever, diarrhea, skin reactions (rash, acne, dry skin, pruritus), loss of appetite, conjunctivitis, blepharitis, dry eye, keratitis, corneal erosion, epistaxis, hematuria, vomiting, nausea, stomatitis, dehydration, dry mouth, pancreatitis, gastrointestinal perforation, increased ALT, increased AST, increased total bilirubin, hepatitis, pustular rash, nail abnormalities, hair loss, angioedema, urticaria, palmar-plantar erythrodysesthesia syndrome, blisters, toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, cutaneous vasculitis, increased serum creatinine, proteinuria, cystitis, hemorrhagic cystitis, weakness, fever, anemia, neutropenia, shortness of breath, pneumonia, increased sputum, pharyngitis, upper respiratory infection, nosebleed, pleural effusion, pain, debility, fatigue, syncope, influenza-like illness, paresthesia, headache, dizziness, neuropathy, seizures, cognitive dysfunction, low back pain, arthralgia, hemoptysis, gum bleeding, petechiae, cerebral infarction, peripheral edema, generalized edema, insomnia, pyuria, chest pain, herpes zoster, visual disturbances, tinnitus

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is advisable to maintain the storage temperature at room temperature between 1 degree and 30 degrees. Proper storage will help maintain its effectiveness and ensure safe use.

Appearance

brown round film-coated tablets

Package unit

30 tablets (10 tablets/PTP*3)