Medication info
Panpyrox Tablet 20mg (Pantoprazole Sodium Sesquihydrate)

Panpyrox Tablet 20mg (Pantoprazole Sodium Sesquihydrate)

Prescription medicationTablet
Ingredient · strength
Pantoprazole Sodium Sesquihydrate›22.55mg / 1 tablet
Manufacturer / importer
Korea Hutech Pharmaceutical Co., Ltd.
Appearance
Yellow enteric-coated oval tablet
Packaging
28 tablets/bottle
Approval status
Active

MFDS item code 201502493 · Approved 2015.04.27 · Insurance code 649102700

Summary

Main use
Treatment of gastroesophageal reflux disease, prevention of recurrence of reflux esophagitis, and prevention of NSAID-induced gastroduodenal ulcers
Who uses it
Adults
Adult dosage
1. Treatment of mild reflux esophageal disease and related symptoms: Administer pantoprazole 20mg orally once daily before breakfast. Symptom relief generally occurs within 2∼4 weeks, and healing can usually be achieved with 4 weeks of treatment. If healing does not occur, it may be achieved with an additional 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Administer pantoprazole 20mg once daily before breakfast. If recurrence occurs, increase the dose to pantoprazole 40mg daily; after healing, reduce it again to 20mg daily. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients who require continuous administration of nonsteroidal anti-inflammatory drugs: Administer pantoprazole 20mg once daily. ◯ No dosage adjustment is necessary in elderly patients or patients with renal impairment. ◯ Patients with hepatic impairment Do not exceed 20mg of this drug once daily in patients with severe hepatic impairment.

Ingredients

Manufacturer
Korea Hutech Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastroesophageal reflux disease, prevention of recurrence of reflux esophagitis, and prevention of NSAID-induced gastroduodenal ulcers

  • Gastroesophageal reflux disease
  • heartburn
  • acid reflux
  • dysphagia
  • reflux esophagitis
  • gastric and duodenal ulcers
View approved original text

This medicine is used to treat mild gastroesophageal reflux disease and symptoms such as heartburn, acid reflux, and dysphagia associated with it. It is also used for long-term maintenance therapy to prevent recurrence of reflux esophagitis. Additionally, those who need to continuously take non-steroidal anti-inflammatory drugs can use this medicine to prevent the occurrence of gastric and duodenal ulcers. It effectively helps improve various gastric-related diseases and symptoms.

Dosage and Administration

Adult dosage

1. Treatment of mild reflux esophageal disease and related symptoms: Administer pantoprazole 20mg orally once daily before breakfast. Symptom relief generally occurs within 2∼4 weeks, and healing can usually be achieved with 4 weeks of treatment. If healing does not occur, it may be achieved with an additional 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Administer pantoprazole 20mg once daily before breakfast. If recurrence occurs, increase the dose to pantoprazole 40mg daily; after healing, reduce it again to 20mg daily. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients who require continuous administration of nonsteroidal anti-inflammatory drugs: Administer pantoprazole 20mg once daily. ◯ No dosage adjustment is necessary in elderly patients or patients with renal impairment. ◯ Patients with hepatic impairment Do not exceed 20mg of this drug once daily in patients with severe hepatic impairment.

Precautions

This medicine should not be used by patients who have had an allergic reaction to this medicine or any of its ingredients. Patients taking certain antiviral medications, specifically atazanavir and nelfinavir, should also not take this medicine. Women in the early stages of pregnancy or those who may become pregnant, as well as breastfeeding women, should not use this medicine. It should also not be administered to patients with genetic issues such as lactose intolerance. This medicine may cause various side effects, which can include abdominal pain, constipation, diarrhea, and nausea in the digestive system. Systemically, fatigue, fever, and swelling may occur, and allergic reactions such as liver dysfunction, skin rashes, and hives have also been reported. Rarely, serious skin diseases or kidney problems may occur. Regular monitoring is necessary for those who take this medicine over a long period, and cessation should occur if liver functions deteriorate. This medicine is not used for mild stomach pain, and caution should be taken as the risk of gastrointestinal bleeding may increase when it is taken with non-steroidal anti-inflammatory drugs. Additionally, long-term use may increase the risk of bone fractures. This medicine suppresses gastric acid secretion and lowers the acidity in the stomach, which can hinder the absorption of certain medications. Therefore, attention should be paid to potential drug interactions, especially when used concurrently with antiviral or anticoagulant medications, and healthcare providers' directions should be followed. The use of this medicine should be avoided in the early stages of pregnancy, and it is advisable for breastfeeding women not to take it. There is insufficient experience for use in children under 12 years of age and therefore it is not recommended. No specific symptoms are known in the event of overdose, but if symptoms occur, treatment should be based on the symptoms. This medicine should be taken whole without chewing or crushing, and in cases of long-term use, appropriate dosage and duration should be determined in consultation with a doctor. When storing, it should be kept out of reach of children and not transferred to other containers.

Side effects

  • Anaphylaxis
  • Anaphylactic shock
  • Angioedema
  • Bronchospasm
  • Acute interstitial nephritis
  • Urticaria
  • Upper abdominal pain
  • Constipation
  • Abdominal distension
  • Diarrhea
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  • Gastric polyps
  • Nausea
  • Vomiting
  • Belching
  • Dry mouth
  • Fatigue
  • Weakness
  • Lethargy
  • Edema
  • Increased body temperature
  • Fever
  • Elevated liver enzyme levels
  • Elevated bilirubin levels
  • Liver failure
  • Arthralgia
  • Myalgia
  • Rhabdomyolysis
  • Bone fractures
  • Headache
  • Dizziness
  • Visual disturbances
  • Taste disturbances
  • Insomnia
  • Sleep disturbances
  • Depression
  • Hallucinations
  • Confusion
  • Disorientation
  • Interstitial nephritis
  • Pruritus
  • Skin erythema
  • Angioedema
  • Stevens-Johnson syndrome
  • Erythema multiforme
  • Toxic epidermal necrolysis
  • Photosensitivity
  • Hyperglycemia
  • Agranulocytosis
  • Leukopenia
  • Thrombocytopenia
  • Pancytopenia
  • Gynecomastia
  • Hyperlipidemia
  • Increased lipids
  • Weight changes
  • Hyponatremia
  • Hypomagnesemia
  • Elevated CK
  • Anxiety
  • Apathy
  • Low back pain
  • Bronchitis
  • Chest pain
  • Increased cough
  • Dyspepsia
  • Dyspnea
  • Influenza-like symptoms
  • Gastroenteritis
  • Gastrointestinal disturbances
  • Tension
  • Infection
  • Migraine
  • Cervical pain
  • Pain
  • Pharyngitis
  • Rectal disturbances
  • Rhinitis
  • Elevated AST
  • Sinusitis
  • Upper respiratory infection
  • Frequent urination
  • Urinary tract infection
  • Boil
  • Allergic reactions
  • Chills
  • Furuncle
  • Facial edema
  • Generalized edema
  • Heat sensation
  • Hernia
  • Abnormal clinical laboratory tests
  • Lethargy
  • Moniliasis
  • Tumor
  • Non-specific drug reactions
  • Electrocardiogram abnormalities
  • Angina
  • Arrhythmia
  • Atrial fibrillation
  • Coronary artery disease
  • Congestive heart failure
  • Hemorrhage
  • Hypertension
  • Hypotension
  • Myocardial infarction
  • Myocardial ischemia
  • Palpitations
  • Retinal vascular disease
  • Syncope
  • Tachycardia
  • Phlebitis
  • Thrombosis
  • Vasodilation
  • Decreased appetite
  • Aphthous stomatitis
  • Colitis
  • Duodenitis
  • Swallowing difficulties
  • Enteritis
  • Esophageal bleeding
  • Esophagitis
  • Gastro-duodenal tumor
  • Gastro-duodenal bleeding
  • Gastro-duodenal moniliasis
  • Gingivitis
  • Halitosis
  • Hematemesis
  • Increased appetite
  • Melena
  • Oral ulcer
  • Oral moniliasis
  • Periodontal abscess
  • Periodontitis
  • Rectal bleeding
  • Gastric ulcer
  • Bowel disturbances
  • Tongue discoloration
  • Ulcerative colitis
  • Diabetes
  • Goiter
  • Gallbladder pain
  • Hyperbilirubinemia
  • Cholecystitis
  • Cholelithiasis
  • Jaundice
  • Hepatitis
  • Elevated ALP
  • Anemia
  • Petechiae
  • Eosinophilia
  • Iron deficiency anemia
  • Leukocytosis
  • Leukopenia
  • Thrombocytopenia
  • Dehydration
  • Gout
  • Thirst
  • Weight gain
  • Weight loss
  • Arthritis
  • Bone diseases
  • Joint diseases
  • Leg cramps
  • Bursitis
  • Tendonitis
  • Abnormal dream
  • Confusion
  • Seizures
  • Dry mouth
  • Speech difficulties
  • Hallucinations
  • Hyperactivity
  • Decreased libido
  • Nervousness
  • Neuralgia
  • Neuritis
  • Neurological disorders
  • Dysesthesia
  • Reduced reflexes
  • Sleep disturbances
  • Drowsiness
  • Altered perception
  • Tremors
  • Asthma
  • Epistaxis
  • Hiccups
  • Laryngitis
  • Respiratory distress
  • Pneumonia
  • Voice changes
  • Acne
  • Alopecia
  • Contact dermatitis
  • Eczema
  • Fungal dermatitis
  • Hemorrhage
  • Herpes simplex
  • Herpes zoster
  • Lichen planus dermatitis
  • Papular rash
  • Skin diseases
  • Skin ulcers
  • Sweating
  • Amblyopia
  • Cataracts
  • Hearing loss
  • Diplopia
  • Ear pain
  • Paralysis
  • Glaucoma
  • Otitis externa
  • Taste disturbances
  • Tinnitus
  • Albuminuria
  • Balanitis
  • Mastalgia
  • Cystitis
  • Menstrual irregularities
  • Urination difficulties
  • Epididymitis
  • Hematuria
  • Erectile dysfunction
  • Renal stones
  • Renal pain
  • Nocturnal enuresis
  • Prostate disorders
  • Pyelonephritis
  • Scrotal edema
  • Urethral pain
  • Urethral diseases
  • Urinary abnormalities
  • Vaginitis
  • Clostridium difficile diarrhea
  • Hypocalcemia
  • Hypokalemia
  • DRESS syndrome
  • Microscopic colitis
  • Systemic lupus erythematosus
  • Cutaneous lupus erythematosus

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine is sensitive to light and should be stored in a light-protective container. Additionally, it should be stored at room temperature, between 1 to 30 degrees Celsius, avoiding extremely hot or cold places.

Appearance and packaging

Appearance

Yellow enteric-coated oval tablet

Package unit

28 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.