Vesicare 5mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including the elderly) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This drug may be taken regardless of meals and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). In patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dose adjustment is necessary in patients with mild hepatic impairment. In patients with moderate hepatic impairment (Child-Pugh class B), administer with caution and do not exceed 5mg once daily. 3. Patients taking strong cytochrome P450 3A4 (CYP3A4) inhibitors In patients taking ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with symptoms of poor urine output. Patients with severe gastrointestinal problems or myasthenia gravis should also not take this medication. Patients with glaucoma or allergies to this medication should avoid administration, as well as patients undergoing dialysis and those with severely impaired liver or kidney function. Additionally, it is safe to avoid administering this medication to patients with certain genetic issues. Caution is advised for patients with a risk of urinary tract obstruction or slow gastrointestinal motility. Patients with moderate kidney or liver impairment should be careful not to exceed the maximum daily dose. Common side effects may include dry mouth, constipation, blurred vision, and dry eyes. Rarely, serious side effects, such as angioedema, allergic reactions, arrhythmias, and liver function abnormalities may occur, so immediate consultation with a healthcare professional is necessary if any unusual symptoms arise. While taking this medication, patients should be cautious of drowsiness or blurred vision that may pose risks during driving or operating machinery. Taking this drug in combination with other anticholinergic medications may enhance effects or increase side effects, so it is essential to inform healthcare providers before taking. When taking drugs that inhibit enzymes that metabolize this medication in the liver, the concentration of this medication may increase, necessitating dosage adjustment. Women who are pregnant or breastfeeding should consult carefully before use, as the safety of this medication has not been established. This medication is not recommended for children, as its safety and efficacy have not been confirmed in this population. In cases of overdose, patients should seek treatment at a hospital immediately, and inducing vomiting is not advisable. Overdose may lead to central nervous system symptoms, respiratory problems, and heart issues, necessitating professional treatment.

• Dry mouth
• constipation
• blurred vision
• urine retention
• dry eyes
• nausea
• dyspepsia
• upper abdominal pain
• vomiting
• urinary tract infection

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to maintain a storage temperature between 1°C and 30°C.

Appearance

Bright yellow round film-coated tablet

Package unit

30 tablets (10 tablets/PTP x 3), 100 tablets (10 tablets/PTP x 10)