Dutokan Soft Capsule 0.5 mg (Dutasteride)

Adult dose

The recommended dose of this drug is 1 capsule (0.5mg) once daily. Because exposure to the capsule contents may cause irritation of the oropharyngeal mucosa, swallow this drug whole without chewing or splitting it. This drug may be taken regardless of meals. No dose adjustment is necessary in patients with renal impairment or elderly patients. Since there are no data on the administration of this drug to patients with hepatic impairment, the recommended dose in these patients has not been established.

This medication can be absorbed through the skin, so it should not be handled or contacted directly, especially by women who are pregnant or may become pregnant. If this medication leaks and comes into contact with the skin, it should be washed off immediately with soap and water. Children should also be kept away from this medication, and if contact occurs, they should be washed immediately. This medication is prohibited for use in women and children under 18 years old. Patients with allergies to this medication or similar ingredients should not take it. Adult men planning to conceive should use this medication cautiously as it may affect fertility, and they should consult a doctor beforehand. Patients with urinary issues or liver dysfunction should use this medication with caution and follow medical advice. Since this medication is metabolized in the liver, patients with liver impairment should be very careful while taking it. Particularly, when taken with strong CYP3A4 enzyme inhibitors, the drug concentration may increase, and should be taken under medical supervision. This medication may cause sexual dysfunction symptoms such as erectile dysfunction, decreased libido, and ejaculatory problems, and in some patients, symptoms may persist even after discontinuation of treatment. Additionally, breast-related adverse reactions such as gynecomastia or breast tenderness have been reported. This medication can affect prostate cancer tests, therefore regular prostate exams and PSA level monitoring are required before and during treatment. While taking this medication, there may be a reduction in PSA levels, so the duration of use should be considered when interpreting PSA levels. Blood donation is prohibited for at least 6 months after taking this medication. There is no specific antidote for overdose; if any symptoms occur, immediate consultation with medical personnel is advised, and appropriate supportive treatment should be received. This medication should be stored out of reach of children and kept in its original container for safety. This medication is known not to affect driving or machinery operation abilities, but there may be individual differences, so caution is necessary.

• erectile dysfunction
• decreased libido
• ejaculation disorder
• gynecomastia
• headache
• gastrointestinal discomfort and pain
• sexual dysfunction
• breast disorders
• dizziness
• rash

This medication should be stored in a tightly closed container to prevent air or moisture ingress and should ideally be kept in a cool place below 30 degrees Celsius. Storing it this way helps maintain its effectiveness for a longer period.

Appearance

Transparent yellowish oval soft capsule containing a colorless transparent liquid

Package unit

30 capsules/box [(15 capsules/PTP × 2)]