Dextrone Tablet 300 mg (Dextibuprofen)

Adult dose

Administer 300 mg of Dexibuprofen orally 2 to 4 times a day. However, do not exceed 1,200 mg of Dexibuprofen in one day.

This medication should be consulted with a doctor or pharmacist before use for those who regularly consume more than three glasses of alcohol daily, as taking this medication increases the risk of gastrointestinal bleeding. Moreover, this medication can affect the cardiovascular system and may increase the risk of serious cardiovascular conditions such as myocardial infarction or stroke. Those with pre-existing cardiovascular diseases or risk factors should exercise caution and closely monitor cardiovascular symptoms with their physician. This medication can cause serious gastrointestinal issues like gastrointestinal bleeding, ulcers, and perforation. Elderly individuals or those with a history of gastrointestinal diseases are at higher risk; thus, if any gastrointestinal symptoms occur during treatment, medical consultation is imperative. Individuals with gastric ulcers or bleeding, severe liver, kidney, or heart disease, and those allergic to this medication or its ingredients should not take this drug. Patients with a history of asthma or allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs also should not take this medication. Co-administration of this medication with aspirin, other non-steroidal anti-inflammatory drugs, or high-dose methotrexate during treatment may pose risks and should be avoided. Dizziness or fatigue may occur when driving or operating machinery, so caution is advised. Pregnant women over six months should not take this medication, and breastfeeding individuals should consult a specialist before use. Before taking this medication, individuals with blood disorders, bleeding tendencies, liver or kidney function issues, hypertension, heart failure, history of hypersensitivity, elderly patients, children (use with caution for those aged 6 and above), and women planning pregnancy should consult a doctor or pharmacist. If serious adverse reactions such as shock, severe skin rashes, difficulty breathing, severe gastrointestinal symptoms, blood disorders, liver dysfunction, kidney dysfunction, or cardiovascular symptoms occur, the medication should be discontinued immediately, and consultation with a healthcare professional is required. This medication should be used at the minimum effective dose for the shortest duration, and regular blood tests along with monitoring of liver and kidney function are necessary for prolonged use. It is also important to remember that this medication is for symptomatic relief and not a causal treatment. Keep this medication out of reach of children, stored in a tightly closed container, away from direct sunlight, and in a cool, dry place. Transferring to another container can lead to quality degradation and accident risks.

Serious side effects

Severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eye membranes, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, markedly reduced urine output, severe systemic edema with increased blood pressure, urticaria, severe allergy

Mild side effects

• Dyspepsia
• abdominal distension
• heartburn
• pain in the upper abdomen
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication with aspirin, other non-steroidal anti-inflammatory drugs, or high-dose (more than 15 mg/week) methotrexate used in cancer therapy. Additionally, avoid concomitant use with corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (such as warfarin), baclofen, and immunosuppressants.

This medication must be stored in a tightly closed container to prevent air and moisture ingress and should be kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

Pink, oval-shaped film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle